1d59

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[[Image:1d59.gif|left|200px]]
[[Image:1d59.gif|left|200px]]
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{{Structure
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|PDB= 1d59 |SIZE=350|CAPTION= <scene name='initialview01'>1d59</scene>, resolution 2.300&Aring;
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The line below this paragraph, containing "STRUCTURE_1d59", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1d59| PDB=1d59 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d59 OCA], [http://www.ebi.ac.uk/pdbsum/1d59 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1d59 RCSB]</span>
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}}
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'''CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA'''
'''CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA'''
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==About this Structure==
==About this Structure==
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1D59 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D59 OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D59 OCA].
==Reference==
==Reference==
Crystal structure of four-stranded Oxytricha telomeric DNA., Kang C, Zhang X, Ratliff R, Moyzis R, Rich A, Nature. 1992 Mar 12;356(6365):126-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1545863 1545863]
Crystal structure of four-stranded Oxytricha telomeric DNA., Kang C, Zhang X, Ratliff R, Moyzis R, Rich A, Nature. 1992 Mar 12;356(6365):126-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1545863 1545863]
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[[Category: Protein complex]]
 
[[Category: Kang, C.]]
[[Category: Kang, C.]]
[[Category: Moyzis, R.]]
[[Category: Moyzis, R.]]
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[[Category: Rich, A.]]
[[Category: Rich, A.]]
[[Category: Zhang, X.]]
[[Category: Zhang, X.]]
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[[Category: loop]]
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[[Category: Loop]]
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[[Category: quadruple helix]]
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[[Category: Quadruple helix]]
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[[Category: tetraplex]]
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[[Category: Tetraplex]]
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[[Category: u-dna]]
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[[Category: U-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:27:55 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:34:56 2008''
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Revision as of 10:27, 2 May 2008

Image:1d59.gif

Template:STRUCTURE 1d59

CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA


Overview

The sequence d(GGGGTTTTGGGG) from the 3' overhang of the Oxytricha telomere has been crystallized and its three-dimensional structure solved to 2.5 A resolution. The oligonucleotide forms hairpins, two of which join to make a four-stranded helical structure with the loops containing four thymine residues at either end. The guanine residues are held together by cyclic hydrogen bonding and an ion is located in the centre. The four guanine residues in each segment have a glycosyl conformation that alternates between anti and syn. There are two four-stranded molecules in the asymmetric unit showing that the structure has some intrinsic flexibility.

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal structure of four-stranded Oxytricha telomeric DNA., Kang C, Zhang X, Ratliff R, Moyzis R, Rich A, Nature. 1992 Mar 12;356(6365):126-31. PMID:1545863 Page seeded by OCA on Fri May 2 13:27:55 2008

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