1n1c

From Proteopedia

(Difference between revisions)

Revision as of 08:43, 2 December 2020

Crystal Structure Of The Dimeric TorD Chaperone From Shewanella Massilia

Structural highlights

1n1c is a 2 chain structure with sequence from 'shewanella massilia'. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
NonStd Res:
Gene:	torD ('Shewanella massilia')
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TORD_SHEMA] Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

TorD is the cytoplasmic chaperone involved in the maturation of the molybdoenzyme TorA prior to the translocation of the folded protein into the periplasm. The X-ray structure at 2.4 A resolution of the TorD dimer reveals extreme domain swapping between the two subunits. The all-helical architecture of the globular domains within the intertwined molecular dimer shows no similarity with known protein structures. According to sequence similarities, this new fold probably represents the architecture of the chaperones associated with the bacterial DMSO/TMAO reductases and also that of proteins of yet unknown functions. The occurrence of multiple oligomeric forms and the chaperone activity of both monomeric and dimeric TorD raise questions about the possible biological role of domain swapping in this protein.

A novel protein fold and extreme domain swapping in the dimeric TorD chaperone from Shewanella massilia.,Tranier S, Iobbi-Nivol C, Birck C, Ilbert M, Mortier-Barriere I, Mejean V, Samama JP Structure. 2003 Feb;11(2):165-74. PMID:12575936^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Tranier S, Iobbi-Nivol C, Birck C, Ilbert M, Mortier-Barriere I, Mejean V, Samama JP. A novel protein fold and extreme domain swapping in the dimeric TorD chaperone from Shewanella massilia. Structure. 2003 Feb;11(2):165-74. PMID:12575936

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1n1c"

@@ Line 1: / Line 1: @@
 ==Crystal Structure Of The Dimeric TorD Chaperone From Shewanella Massilia==
-<StructureSection load='1n1c' size='340' side='right' caption='[[1n1c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='1n1c' size='340' side='right'caption='[[1n1c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1n1c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'shewanella_massilia' 'shewanella massilia']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N1C FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1n1c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'shewanella_massilia' 'shewanella massilia']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1N1C FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene></td></tr>
 <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">torD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=76854 'Shewanella massilia'])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n1c OCA], [http://pdbe.org/1n1c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1n1c RCSB], [http://www.ebi.ac.uk/pdbsum/1n1c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1n1c ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1n1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n1c OCA], [http://pdbe.org/1n1c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1n1c RCSB], [http://www.ebi.ac.uk/pdbsum/1n1c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1n1c ProSAT]</span></td></tr>
 </table>
 == Function ==
@@ Line 15: / Line 15: @@
 Check<jmol>
   <jmolCheckbox>
-    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n1/1n1c_consurf.spt"</scriptWhenChecked>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n1/1n1c_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 35: / Line 35: @@
 </StructureSection>
 [[Category: Shewanella massilia]]
+[[Category: Large Structures]]
 [[Category: Birck, C]]
 [[Category: Iobbi-Nivol, C]]

1n1c

From Proteopedia

Revision as of 08:43, 2 December 2020

Crystal Structure Of The Dimeric TorD Chaperone From Shewanella Massilia

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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