1nz8

From Proteopedia

(Difference between revisions)

Revision as of 09:00, 2 December 2020

Solution Structure of the N-utilization substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus

Structural highlights

1nz8 is a 1 chain structure with sequence from "flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Related:	1nz9
Gene:	NusG ("Flavobacterium thermophilum" Yoshida and Oshima 1971)
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[NUSG_THET8] Participates in transcription elongation, termination and antitermination (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

NusG is an essential bacterial protein modulator of transcriptional elongation and termination events, and interacts directly with RNA polymerase and Rho protein. Found also in Archaea, NusG shows stretches of sequence similarity to the eukaryotic transcription elongation factor Spt5. Herein, the three-dimensional solution structure of the bacterial NusG from Thermus thermophilus, which shows 43% amino acid sequence similarity to the Escherichia coli NusG, is described, and a survey of NusG and Spt5 amino acid sequences is presented. Although there is a clear evolutionary and functional relationship between these proteins, it is evident from the structural, sequence, and biochemical data that their binding specificities to both nucleic acids and other proteins differ.

Structural and sequence comparisons arising from the solution structure of the transcription elongation factor NusG from Thermus thermophilus.,Reay P, Yamasaki K, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S Proteins. 2004 Jul 1;56(1):40-51. PMID:15162485^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Reay P, Yamasaki K, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S. Structural and sequence comparisons arising from the solution structure of the transcription elongation factor NusG from Thermus thermophilus. Proteins. 2004 Jul 1;56(1):40-51. PMID:15162485 doi:10.1002/prot.20054

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1nz8"

@@ Line 1: / Line 1: @@
 ==Solution Structure of the N-utilization substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus==
-<StructureSection load='1nz8' size='340' side='right' caption='[[1nz8]], [[NMR_Ensembles_of_Models | 31 NMR models]]' scene=''>
+<StructureSection load='1nz8' size='340' side='right'caption='[[1nz8]], [[NMR_Ensembles_of_Models | 31 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1nz8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZ8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1nz8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZ8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1NZ8 FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nz9|1nz9]]</td></tr>
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nz9|1nz9]]</div></td></tr>
 <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NusG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 "Flavobacterium thermophilum" Yoshida and Oshima 1971])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nz8 OCA], [http://pdbe.org/1nz8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nz8 RCSB], [http://www.ebi.ac.uk/pdbsum/1nz8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nz8 ProSAT], [http://www.topsan.org/Proteins/RSGI/1nz8 TOPSAN]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1nz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nz8 OCA], [http://pdbe.org/1nz8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nz8 RCSB], [http://www.ebi.ac.uk/pdbsum/1nz8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nz8 ProSAT], [http://www.topsan.org/Proteins/RSGI/1nz8 TOPSAN]</span></td></tr>
 </table>
 == Function ==
@@ Line 34: / Line 34: @@
 </StructureSection>
 [[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
+[[Category: Large Structures]]
 [[Category: Kuramitsu, S]]
 [[Category: Structural genomic]]

1nz8

From Proteopedia

Revision as of 09:00, 2 December 2020

Solution Structure of the N-utilization substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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