This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Toll-like Receptor 3D structures

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 4: Line 4:
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
-
*Toll-like receptor 1
+
*Toll-like receptor 1; Domains – TIR 625-785; ligand-binding (LBD) 22-703; transmembrane 698-730
**[[1fyv]] – hTLR1 TIR domain – human<br />
**[[1fyv]] – hTLR1 TIR domain – human<br />
 +
**[[6nih]] - hTLR1/VLRB.61<br />
**[[2z7x]], [[2z81]], [[2z82]] – hTLR1/VLRB.61 + hTLR2/VLRB.61 + lipopeptide
**[[2z7x]], [[2z81]], [[2z82]] – hTLR1/VLRB.61 + hTLR2/VLRB.61 + lipopeptide
Line 15: Line 16:
**[[2z80]] – hTLR2/VLRB.61<br />
**[[2z80]] – hTLR2/VLRB.61<br />
**[[3a79]] – hTLR2/VLRB.61 + hTLR6/VLRB.61 + lipopeptide<br />
**[[3a79]] – hTLR2/VLRB.61 + hTLR6/VLRB.61 + lipopeptide<br />
 +
**[[6nig]] – hTLR2/VLRB.61 + diprovocim<br />
**[[3a7b]] - mTLR2/VLRB.61 – mouse<br />
**[[3a7b]] - mTLR2/VLRB.61 – mouse<br />
**[[3a7c]] - mTLR2/VLRB.61 + PE-DTPA<br />
**[[3a7c]] - mTLR2/VLRB.61 + PE-DTPA<br />
Line 21: Line 23:
*Toll-like receptor 3
*Toll-like receptor 3
-
**[[1ziw]], [[2a0z]] – hTLR3 ligand-binding domain<br />
+
**[[1ziw]], [[2a0z]] – hTLR3 LBD<br />
**[[5gs0]] – hTLR3 ectodomain + antibody<br />
**[[5gs0]] – hTLR3 ectodomain + antibody<br />
**[[2mk9]], [[2mka]] – hTLR3 transmembrane domain - NMR <br />
**[[2mk9]], [[2mka]] – hTLR3 transmembrane domain - NMR <br />
-
**[[3cig]] – mTLR3 ectodomain<br />
+
**[[3ulv]], [[3ulu]], [[5gs0]] – hTLR3 LBD + antibody<br />
-
**[[3ciy]] - mTLR3 ectodomain + RNA<br />
+
**[[3cig]] – mTLR3 LBD<br />
 +
**[[3ciy]] - mTLR3 LBD + RNA<br />
*Toll-like receptor 4
*Toll-like receptor 4
Line 32: Line 35:
**[[3ul8]], [[3ul7]] – hTLR4/VLRB.61 (mutant)<br />
**[[3ul8]], [[3ul7]] – hTLR4/VLRB.61 (mutant)<br />
**[[5nam]], [[5nao]] – hTLR4 transmembrane domain - NMR<br />
**[[5nam]], [[5nao]] – hTLR4 transmembrane domain - NMR<br />
-
**[[3fxi]], [[4g8a]] - hTLR4 extracellular domain + lymphocyte antigen 96<br />
+
**[[3fxi]], [[4g8a]] - hTLR4 LBD + lymphocyte antigen 96<br />
**[[3ula]] - hTLR4/VLRB.61 + lymphocyte antigen 96<br />
**[[3ula]] - hTLR4/VLRB.61 + lymphocyte antigen 96<br />
-
**[[2z64]], [[2z65]], [[5ijc]], [[5ijd]], [[3vq1]], [[3vq2]] – mTLR4 extracellular domain+ lymphocyte antigen 96<br />
+
**[[2z64]], [[2z65]], [[5ijc]], [[5ijd]], [[3vq1]], [[3vq2]] – mTLR4 LBD + lymphocyte antigen 96<br />
 +
 
 +
*Toll-like receptor 5
 +
 
 +
**[[3j0a]] – hTLR5<br />
*Toll-like receptor 5B
*Toll-like receptor 5B
Line 41: Line 48:
**[[6bxa]] – zfTLR5B N-terminal + VLR2 <br />
**[[6bxa]] – zfTLR5B N-terminal + VLR2 <br />
**[[6bxc]] – zfTLR5B N-terminal + VLR9 <br />
**[[6bxc]] – zfTLR5B N-terminal + VLR9 <br />
-
**[[3v44]] – zfTLR5B/VLRB.61 <br />
+
**[[3v44]], [[6bxa]], [[6bxc]] – zfTLR5B/VLRB.61 <br />
**[[3v47]] – zfTLR5B/VLRB.61 + flagellin<br />
**[[3v47]] – zfTLR5B/VLRB.61 + flagellin<br />
Line 50: Line 57:
*Toll-like receptor 7
*Toll-like receptor 7
-
**[[5gmf]] – mTLR7 + guanosine + poly-U - monkey <br />
+
**[[5gmf]] – moTLR7 + guanosine + poly-U - monkey <br />
-
**[[5gmg]] – mTLR7 + loxoribine + poly-U <br />
+
**[[5gmg]] – moTLR7 + loxoribine + poly-U <br />
-
**[[5gmh]] – mTLR7 + resiquimod + poly-U <br />
+
**[[5gmh]] – moTLR7 + resiquimod + poly-U <br />
*Toll-like receptor 8
*Toll-like receptor 8
Line 70: Line 77:
**[[3wpg]], [[3wph]], [[3wpi]] – mTLR9 + DNA <br />
**[[3wpg]], [[3wph]], [[3wpi]] – mTLR9 + DNA <br />
**[[5zln]] – mTLR9 (mutant) + DNA <br />
**[[5zln]] – mTLR9 (mutant) + DNA <br />
 +
**[[4qdh]] – mTLR9/VLRB.61 <br />
*Toll-like receptor 10
*Toll-like receptor 10

Revision as of 09:17, 6 December 2020

3D Structures of Toll-like Receptors

Updated on 06-December-2020 - For a general description of the protein see Toll-like Receptors

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

Personal tools