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Sandbox Reserved 1636
From Proteopedia
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== Function of your Protein == | == Function of your Protein == | ||
| - | my protein is <scene name='86/861618/Protein_view_2/5 | + | my protein is <scene name='86/861618/Protein_view_2/5'>Flavin, it is found in fungus. it is sort of an enzyme and a receptor at the same time, and it helps grab metals. so, its job is to provide iron which is a critical nutrient used by fungus. |
since it acts as a receptor as well, it does interact with NADH. </scene> | since it acts as a receptor as well, it does interact with NADH. </scene> | ||
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== Biological relevance and broader implications == | == Biological relevance and broader implications == | ||
| - | the journal article is exploring the role of flavin FAD and how fungi uses FAD in the reaction, as it takes ornithine to hydroxyl ornithine (redox reaction), in order to grab the iron needed, because the bioavailability or iron in the environment is extremely limited due to its existence as insoluble ferric oxide. | ||
| - | this journal article also discussed Aspergillosis which is a condition in which Aspergillus Fumigatus infects the lungs causing fatal mycoses in humans as well as animals, resulting n about 200,000 cases in humans each year, and about half of this number deaths. | ||
| - | so, it is really important to study this protein and understand the mechanism with which it works and help the fungus infect in order to fight these infections and discover a new antifungal drug that works better for both human and animals. | ||
== Important amino acids == | == Important amino acids == | ||
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== Structural highlights == | == Structural highlights == | ||
Revision as of 19:59, 6 December 2020
| This Sandbox is Reserved from 09/18/2020 through 03/20/2021 for use in CHEM 351 Biochemistry taught by Bonnie Hall at Grand View University, Des Moines, IA. This reservation includes Sandbox Reserved 1628 through Sandbox Reserved 1642. |
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
