Sandbox Reserved 1636
From Proteopedia
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since it acts as a receptor as well, it does interact with NADH. </scene> | since it acts as a receptor as well, it does interact with NADH. </scene> | ||
== Biological relevance and broader implications == | == Biological relevance and broader implications == | ||
| - | + | this journal article is explaining the role of flavin FAD and how fungi uses it in the redox reaction as it takes ornithine to hydroxyornithine in order to grab the iron needed, because the bioavailability of iron in the environment is extremely limited. | |
| + | this journal article also discussed Aspergillosis, which is a condition in which Aspergillus fumigatus infects the lungs causing fatal mycoses in humans as well as animals resulting in about 200,000 cases per year, in humans only, and it cases death in about half of this number. | ||
| + | So, it is really important to study this protein and understands the mechanism with which it works in order to fight the infection and discover a new anti-fungal drug that will work better for both humans and animals. | ||
== Important amino acids == | == Important amino acids == | ||
Revision as of 20:14, 6 December 2020
| This Sandbox is Reserved from 09/18/2020 through 03/20/2021 for use in CHEM 351 Biochemistry taught by Bonnie Hall at Grand View University, Des Moines, IA. This reservation includes Sandbox Reserved 1628 through Sandbox Reserved 1642. |
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References
journal article: Trapping conformational states of a flavin-dependent N-monooxygenase in crystallo reveals protein and flavin dynamics
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
