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1orf

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==The Oligomeric Structure of Human Granzyme A Reveals the Molecular Determinants of Substrate Specificity==
==The Oligomeric Structure of Human Granzyme A Reveals the Molecular Determinants of Substrate Specificity==
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<StructureSection load='1orf' size='340' side='right' caption='[[1orf]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='1orf' size='340' side='right'caption='[[1orf]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1orf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ORF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ORF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1orf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ORF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1ORF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0G6:D-PHENYLALANYL-N-[(2S,3S)-6-{[AMINO(IMINIO)METHYL]AMINO}-1-CHLORO-2-HYDROXYHEXAN-3-YL]-L-PROLINAMIDE'>0G6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0G6:D-PHENYLALANYL-N-[(2S,3S)-6-{[AMINO(IMINIO)METHYL]AMINO}-1-CHLORO-2-HYDROXYHEXAN-3-YL]-L-PROLINAMIDE'>0G6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GZMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GZMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Granzyme_A Granzyme A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.78 3.4.21.78] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Granzyme_A Granzyme A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.78 3.4.21.78] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1orf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1orf OCA], [http://pdbe.org/1orf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1orf RCSB], [http://www.ebi.ac.uk/pdbsum/1orf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1orf ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1orf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1orf OCA], [http://pdbe.org/1orf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1orf RCSB], [http://www.ebi.ac.uk/pdbsum/1orf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1orf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 1orf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1orf" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Granzyme|Granzyme]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Granzyme A]]
[[Category: Granzyme A]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Bell, J K]]
[[Category: Bell, J K]]
[[Category: Craik, C S]]
[[Category: Craik, C S]]

Revision as of 07:14, 9 December 2020

The Oligomeric Structure of Human Granzyme A Reveals the Molecular Determinants of Substrate Specificity

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