1d96

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[[Image:1d96.gif|left|200px]]
[[Image:1d96.gif|left|200px]]
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{{Structure
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|PDB= 1d96 |SIZE=350|CAPTION= <scene name='initialview01'>1d96</scene>, resolution 2.000&Aring;
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The line below this paragraph, containing "STRUCTURE_1d96", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>
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{{STRUCTURE_1d96| PDB=1d96 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d96 OCA], [http://www.ebi.ac.uk/pdbsum/1d96 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1d96 RCSB]</span>
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'''MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA'''
'''MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA'''
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==About this Structure==
==About this Structure==
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1D96 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D96 OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D96 OCA].
==Reference==
==Reference==
Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6181416 6181416]
Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6181416 6181416]
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[[Category: Protein complex]]
 
[[Category: Boeckel, S A.A Van.]]
[[Category: Boeckel, S A.A Van.]]
[[Category: Boom, J H.Van.]]
[[Category: Boom, J H.Van.]]
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[[Category: Rich, A.]]
[[Category: Rich, A.]]
[[Category: Wang, A H.J.]]
[[Category: Wang, A H.J.]]
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[[Category: a-dna/rna]]
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[[Category: A-dna/rna]]
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[[Category: double helix]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:35:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:37:01 2008''
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Revision as of 10:35, 2 May 2008

Image:1d96.gif

Template:STRUCTURE 1d96

MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA


Overview

The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA hybrid segments surrounding a central region of double helical DNA; its molecular structure has been solved by X-ray analysis. All three parts of the molecule adopt a conformation which is close to that seen in the 11-fold RNA double helix. The conformation of the ribonucleotides is partly determined by water molecules bridging between the ribose O2' hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no structural discontinuities. However, the central DNA TATA sequence has some structural irregularities.

About this Structure

Full crystallographic information is available from OCA.

Reference

Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:6181416 Page seeded by OCA on Fri May 2 13:35:24 2008

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