This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Transferrin receptor

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 9: Line 9:
</StructureSection>
</StructureSection>
==3D structures of transferrin receptor==
==3D structures of transferrin receptor==
 +
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
 +
Domains – apical 197-378; ectodomain 121-760
[[1cx8]] – hTfR ectodomain – human<br />
[[1cx8]] – hTfR ectodomain – human<br />
 +
[[6y76]] - hTfR apical domain <br />
[[1de4]] - hTfR ectodomain + hemochromatosis protein + β-2-microglobulin<br />
[[1de4]] - hTfR ectodomain + hemochromatosis protein + β-2-microglobulin<br />
[[1suv]], [[6soy]], [[6soz]] - hTfR ectodomain + transferrin<br />
[[1suv]], [[6soy]], [[6soz]] - hTfR ectodomain + transferrin<br />
 +
[[6okd]] - hTfR ectodomain + TfR-binding cysteine-dense peptide<br />
[[6d03]], [[6d04]], [[6d05]] - hTfR ectodomain + transferrin – Cryo EM<br />
[[6d03]], [[6d04]], [[6d05]] - hTfR ectodomain + transferrin – Cryo EM<br />
 +
[[6gsr]], [[6h5i]] - hTfR ectodomain + ferritin heavy chain – Cryo EM<br />
[[6s9j]] - hTfR ectodomain + PRE-GP-C<br />
[[6s9j]] - hTfR ectodomain + PRE-GP-C<br />
[[3s9l]], [[3s9m]], [[3s9n]] - hTfR ectodomain + transferrin N-lobe<br />
[[3s9l]], [[3s9m]], [[3s9n]] - hTfR ectodomain + transferrin N-lobe<br />

Revision as of 08:33, 14 December 2020

Human transferrin receptor ectodomain dimer (grey and green) complex with transferrin N-lobe (pink and yellow) and C-lobe (cyan and magenta) and carbonate, 1suv

Drag the structure with the mouse to rotate

3D structures of transferrin receptor

Updated on 14-December-2020

Domains – apical 197-378; ectodomain 121-760

1cx8 – hTfR ectodomain – human
6y76 - hTfR apical domain
1de4 - hTfR ectodomain + hemochromatosis protein + β-2-microglobulin
1suv, 6soy, 6soz - hTfR ectodomain + transferrin
6okd - hTfR ectodomain + TfR-binding cysteine-dense peptide
6d03, 6d04, 6d05 - hTfR ectodomain + transferrin – Cryo EM
6gsr, 6h5i - hTfR ectodomain + ferritin heavy chain – Cryo EM
6s9j - hTfR ectodomain + PRE-GP-C
3s9l, 3s9m, 3s9n - hTfR ectodomain + transferrin N-lobe
2nsu - hTfR ectodomain in dog retrovirus – Cryo EM
3kas - hTfR ectodomain + Machupo virus GP1

References

  1. ↑ Levy JE, Jin O, Fujiwara Y, Kuo F, Andrews NC. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet. 1999 Apr;21(4):396-9. PMID:10192390 doi:http://dx.doi.org/10.1038/7727
  2. ↑ Cazzola M, Beguin Y, Bergamaschi G, Guarnone R, Cerani P, Barella S, Cao A, Galanello R. Soluble transferrin receptor as a potential determinant of iron loading in congenital anaemias due to ineffective erythropoiesis. Br J Haematol. 1999 Sep;106(3):752-5. PMID:10468869

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Transferrin_receptor"
Personal tools