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6o6e
From Proteopedia
(Difference between revisions)
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/PLTF_PSEF5 PLTF_PSEF5]] Involved in the biosynthesis of pyoluteorin. Catalyzes the conversion of L-proline to L-prolyl-AMP and the transfer of the L-prolyl group to acyl carrier protein PltL.<ref>PMID:11880032</ref> | [[http://www.uniprot.org/uniprot/PLTF_PSEF5 PLTF_PSEF5]] Involved in the biosynthesis of pyoluteorin. Catalyzes the conversion of L-proline to L-prolyl-AMP and the transfer of the L-prolyl group to acyl carrier protein PltL.<ref>PMID:11880032</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Using a covalent chemical probe and X-ray crystallography coupled to nuclear magnetic resonance data, we elucidated the dynamic molecular basis of protein recognition between the carrier protein and adenylation domain in pyoluteorin biosynthesis. These findings reveal a unique binding mode, which contrasts previously solved carrier protein and partner protein interfaces. | ||
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| + | Dynamic visualization of type II peptidyl carrier protein recognition in pyoluteorin biosynthesis.,Corpuz JC, Podust LM, Davis TD, Jaremko MJ, Burkart MD RSC chem biol. 2020 Apr 1;1(1):8-12. doi: 10.1039/c9cb00015a. Epub 2020 Mar 24. PMID:33305272<ref>PMID:33305272</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6o6e" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 10:50, 24 December 2020
Crystal structure of PltF trapped with PltL using a proline adenosine vinylsulfonamide inhibitor
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