1dd9
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1dd9.jpg|left|200px]] | [[Image:1dd9.jpg|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1dd9", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |
| - | | | + | or leave the SCENE parameter empty for the default display. |
| - | | | + | --> |
| - | + | {{STRUCTURE_1dd9| PDB=1dd9 | SCENE= }} | |
| - | + | ||
| - | + | ||
| - | }} | + | |
'''STRUCTURE OF THE DNAG CATALYTIC CORE''' | '''STRUCTURE OF THE DNAG CATALYTIC CORE''' | ||
| Line 30: | Line 27: | ||
[[Category: Roche, D D.]] | [[Category: Roche, D D.]] | ||
[[Category: 3-helix bundle]] | [[Category: 3-helix bundle]] | ||
| - | [[Category: | + | [[Category: Dna-binding protein]] |
| - | [[Category: | + | [[Category: Primase]] |
| - | [[Category: | + | [[Category: Replication protein]] |
| - | [[Category: | + | [[Category: Rna polymerase]] |
| - | [[Category: | + | [[Category: Toprim]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:43:09 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 10:43, 2 May 2008
STRUCTURE OF THE DNAG CATALYTIC CORE
Overview
All cellular organisms use specialized RNA polymerases called "primases" to synthesize RNA primers for the initiation of DNA replication. The high-resolution crystal structure of a primase, comprising the catalytic core of the Escherichia coli DnaG protein, was determined. The core structure contains an active-site architecture that is unrelated to other DNA or RNA polymerase palm folds, but is instead related to the "toprim" fold. On the basis of the structure, it is likely that DnaG binds nucleic acid in a groove clustered with invariant residues and that DnaG is positioned within the replisome to accept single-stranded DNA directly from the replicative helicase.
About this Structure
1DD9 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Structure of the RNA polymerase domain of E. coli primase., Keck JL, Roche DD, Lynch AS, Berger JM, Science. 2000 Mar 31;287(5462):2482-6. PMID:10741967 Page seeded by OCA on Fri May 2 13:43:09 2008
