1tp0

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==Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan.==
==Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan.==
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<StructureSection load='1tp0' size='340' side='right' caption='[[1tp0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='1tp0' size='340' side='right'caption='[[1tp0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1tp0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TP0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TP0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1tp0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TP0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1TP0 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1s0l|1s0l]], [[1t4q|1t4q]], [[1too|1too]], [[1twe|1twe]], [[1twm|1twm]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1s0l|1s0l]], [[1t4q|1t4q]], [[1too|1too]], [[1twe|1twe]], [[1twm|1twm]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tp0 OCA], [http://pdbe.org/1tp0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tp0 RCSB], [http://www.ebi.ac.uk/pdbsum/1tp0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tp0 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1tp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tp0 OCA], [http://pdbe.org/1tp0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tp0 RCSB], [http://www.ebi.ac.uk/pdbsum/1tp0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tp0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tp/1tp0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tp/1tp0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Interleukin|Interleukin]]
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*[[Interleukin 3D structures|Interleukin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Adamek, D H]]
[[Category: Adamek, D H]]
[[Category: Caspar, D L]]
[[Category: Caspar, D L]]

Revision as of 11:57, 24 December 2020

Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan.

PDB ID 1tp0

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