This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Ubiquitin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 23: Line 23:
**[[2zcb]], [[2gbj]], [[2gbk]], [[2gbm]], [[2gbn]], [[2gbr]], [[2fcm]], [[2fcn]], [[2fcs]], [[1yiw]], [[1yj1]], [[1sif]], [[1ogw]], [[4hk2]], [[4hjk]], [[4pij]], [[4pih]], [[4pig]] - hUBB (mutant)<br />
**[[2zcb]], [[2gbj]], [[2gbk]], [[2gbm]], [[2gbn]], [[2gbr]], [[2fcm]], [[2fcn]], [[2fcs]], [[1yiw]], [[1yj1]], [[1sif]], [[1ogw]], [[4hk2]], [[4hjk]], [[4pij]], [[4pih]], [[4pig]] - hUBB (mutant)<br />
**[[2kn5]], [[2klg]], [[2jzz]], [[2pe9]], [[2pea]], [[1g6j]], [[1d3z]], [[2kox]], [[2ld9]], [[2k25]], [[5ujl]], [[6v5d]] – hUBB – NMR<br />
**[[2kn5]], [[2klg]], [[2jzz]], [[2pe9]], [[2pea]], [[1g6j]], [[1d3z]], [[2kox]], [[2ld9]], [[2k25]], [[5ujl]], [[6v5d]] – hUBB – NMR<br />
-
**[[1c3t]], [[1ud7]], [[2mi8]], [[2rsu]], [[2ru6]], [[6k4i]] - hUBB (mutant) - NMR<br />
+
**[[1c3t]], [[1ud7]], [[2mi8]], [[2rsu]], [[2ru6]], [[6k4i]], [[5zd0]] - hUBB (mutant) - NMR<br />
**[[2m0x]] - hUBB - engineered – NMR<br />
**[[2m0x]] - hUBB - engineered – NMR<br />
**[[6gf1]] - hUBB D<br />
**[[6gf1]] - hUBB D<br />
Line 76: Line 76:
* Ubiquitin trimer
* Ubiquitin trimer
-
**[[5go7]], [[5gok]], [[5jby]], [[5jbv]], [[6oq1]] – hTriUBB <br />
+
**[[5go7]], [[5gok]], [[5jby]], [[5jbv]], [[6oq1]], [[7cap]] – hTriUBB <br />
**[[3zlz]], [[5o44]] – hTriUBB (mutant) <br />
**[[3zlz]], [[5o44]] – hTriUBB (mutant) <br />
**[[6oq2]] – hTriUBB - NMR<br />
**[[6oq2]] – hTriUBB - NMR<br />
Line 84: Line 84:
* Ubiquitin tetramer
* Ubiquitin tetramer
-
**[[5go8]] – hTetraUBB <br />
+
**[[5go8]], [[5xdp]] – hTetraUBB <br />
**[[3tmp]] – hTetraUBB + deubiquitinase<br />
**[[3tmp]] – hTetraUBB + deubiquitinase<br />
**[[3alb]], [[3hm3]], [[2o6v]], [[1f9j]], [[1tbe]] – tetra-hUBB<br />
**[[3alb]], [[3hm3]], [[2o6v]], [[1f9j]], [[1tbe]] – tetra-hUBB<br />
Line 93: Line 93:
* Polyubiquitin-B
* Polyubiquitin-B
-
**[[6nxl]] – hUBB<br />
+
**[[6nxl]], [[5x3n]] – hUBB<br />
**[[4zpz]], [[6qk9]], [[5w46]] – hUBB (mutant)<br />
**[[4zpz]], [[6qk9]], [[5w46]] – hUBB (mutant)<br />
-
**[[5x3o]], [[3x3m]] – hUBB + d-ubiquitin <br />
+
**[[5xk5]], [[6kow]], [[6kox]], [[6qf8]] – hUBB - NMR<br />
 +
**[[5x3m]], [[5x3o]], [[3x3m]] – hUBB + d-ubiquitin <br />
**[[3phd]] – hUBB + histone deacetylase 6
**[[3phd]] – hUBB + histone deacetylase 6
**[[3znh]] – hUBB + UBB thioesterase<br />
**[[3znh]] – hUBB + UBB thioesterase<br />
 +
**[[7jms]] – hUBB + UBB replicase<br />
**[[5ydr]] – hUBB + DNMT1<br />
**[[5ydr]] – hUBB + DNMT1<br />
-
**[[6fdk]] – hUBB + DUB1<br />
+
**[[6fdk]], [[6gzs]] – hUBB + Dub1<br />
**[[6ei1]], [[6fge]] – hUBB + ZUP1<br />
**[[6ei1]], [[6fge]] – hUBB + ZUP1<br />
 +
**[[6ei1]] – hUBB + ZUFSP<br />
**[[6cp2]] – hUBB + UbcH7 + SidC<br />
**[[6cp2]] – hUBB + UbcH7 + SidC<br />
**[[6bva]], [[6byh]], [[6c16]] – hUBB + SKP1 + FBL10<br />
**[[6bva]], [[6byh]], [[6c16]] – hUBB + SKP1 + FBL10<br />
Line 132: Line 135:
**[[4k1r]] – hUBC + SST2<br />
**[[4k1r]] – hUBC + SST2<br />
**[[5oe7]] – hUBC + otulin<br />
**[[5oe7]] – hUBC + otulin<br />
 +
**[[6kbe]] – hUBC + UBB thioesterase<br />
**[[6b7m]], [[6b70]] – hUBC + SDED<br />
**[[6b7m]], [[6b70]] – hUBC + SDED<br />
**[[6aqr]] – hUBC + SAGA + UBP8 + SGF11 + SUS1 + SGF73<br />
**[[6aqr]] – hUBC + SAGA + UBP8 + SGF11 + SUS1 + SGF73<br />
Line 139: Line 143:
**[[6rya]] – hUBC + Dup1<br />
**[[6rya]] – hUBC + Dup1<br />
**[[6b7o]] – hUBC + SdeD<br />
**[[6b7o]] – hUBC + SdeD<br />
 +
**[[6ypt]] – hUBC + RNA replicase<br />
 +
**[[6tnf]] – hUBC + FANCI + FANCD2 + DNA - Cryo EM<br />
* Ubiquitin monomer bound to protein
* Ubiquitin monomer bound to protein
Line 151: Line 157:
**[[2z59]] – hUBB+mProtein Adhesion-regulating molecule 1<br />
**[[2z59]] – hUBB+mProtein Adhesion-regulating molecule 1<br />
**[[2jy6]] – hUBB+hUbiquilin – NMR<br />
**[[2jy6]] – hUBB+hUbiquilin – NMR<br />
-
**[[3by4]], [[3c0r]] – hUBB+yUBB thioesterase<br />
+
**[[3by4]], [[3c0r]], [[6k9p]] – hUBB+ UBB thioesterase<br />
**[[2hth]] – hUBB+vacuolar protein sorting protein<br />
**[[2hth]] – hUBB+vacuolar protein sorting protein<br />
**[[1s1q]] – hUBB+tumor susceptibility gene 101 protein<br />
**[[1s1q]] – hUBB+tumor susceptibility gene 101 protein<br />
Line 188: Line 194:
**[[6b7m]] – hUBB + SdeD<br />
**[[6b7m]] – hUBB + SdeD<br />
**[[5ydr]] – hUBB + DNMT1<br />
**[[5ydr]] – hUBB + DNMT1<br />
 +
**[[5xpk]] – hUBB + D-UBB<br />
**[[6ob1]] – hUBB + WHB - NMR<br />
**[[6ob1]] – hUBB + WHB - NMR<br />
**[[4un2]] – hUBB + Dsk2 peptide<br />
**[[4un2]] – hUBB + Dsk2 peptide<br />
Line 205: Line 212:
**[[4msq]], [[4msm]] – hUBB + AMSH-like protease<br />
**[[4msq]], [[4msm]] – hUBB + AMSH-like protease<br />
**[[6upu]] – hUBB + otDUB<br />
**[[6upu]] – hUBB + otDUB<br />
-
**[[6ttu]] – hUBB in cullin-ring-ube2d assembly - Cryo EM<br />
+
**[[6pgv]] – hUBB + Josephine 2<br />
**[[4m0w]] – bUBB + replicase polyprotein<br />
**[[4m0w]] – bUBB + replicase polyprotein<br />
**[[1uzx]] – bUBB+VPS23 UEV<br />
**[[1uzx]] – bUBB+VPS23 UEV<br />
Line 233: Line 240:
**[[5v1z]], [[5v1y]], [[6oi4]] – hUBB + RPN13 + RPN2<br />
**[[5v1z]], [[5v1y]], [[6oi4]] – hUBB + RPN13 + RPN2<br />
**[[6eqi]] – hUBB + Nb696 + PINK1<br />
**[[6eqi]] – hUBB + Nb696 + PINK1<br />
-
**[[5wvo]] – hUBB + DNMT1 + histone H3.1<br />
+
**[[5wvo]], [[6pzv]] – hUBB + DNMT1 + histone<br />
**[[6oaa]], [[6oa9]] – yUBB + Npl4 + cdc48 - Cryo EM<br />
**[[6oaa]], [[6oa9]] – yUBB + Npl4 + cdc48 - Cryo EM<br />
 +
**[[6t9l]] – hUBB in SAGA DUB module - Cryo EM<br />
 +
**[[6wjd]], [[6wjn]], [[6ef0]], [[6ef1]], [[6ef2]] – hUBB in 26S proteasome - Cryo EM<br />
 +
**[[6ttu]] – hUBB in cullin-ring-ube2d assembly - Cryo EM<br />
 +
**[[6nj9]], [[6nog]], [[6nqa]], [[6jma]], [[6ven]], [[6j99]] – hUBB in nucleosome - Cryo EM<br />
 +
**[[6xiq]] – hUBB (mutant) in ribosome - Cryo EM<br />
 +
**[[6vae]], [[6vaf]] – hUBB + FANCI + FANCD2 + DNA<br />
* Ubiquitin complex with ubiquitination enzymes
* Ubiquitin complex with ubiquitination enzymes

Revision as of 10:22, 3 January 2021

Human ubiquitin (green) complex with ubiquitin-conjugating enzyme E2 (deep sky blue), 3k9p

Drag the structure with the mouse to rotate

3D Structures of Ubiquitin

Updated on 03-January-2021

References

  1. ↑ Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem. 1998;67:425-79. PMID:9759494 doi:http://dx.doi.org/10.1146/annurev.biochem.67.1.425
  2. ↑ Paul S. Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches. Bioessays. 2008 Nov;30(11-12):1172-84. doi: 10.1002/bies.20852. PMID:18937370 doi:http://dx.doi.org/10.1002/bies.20852
Retrieved from "http://52.214.119.220/wiki/index.php/Ubiquitin"
Personal tools