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1x86

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==Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA==
==Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA==
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<StructureSection load='1x86' size='340' side='right' caption='[[1x86]], [[Resolution|resolution]] 3.22&Aring;' scene=''>
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<StructureSection load='1x86' size='340' side='right'caption='[[1x86]], [[Resolution|resolution]] 3.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1x86]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X86 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X86 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1x86]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X86 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1X86 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1txd|1txd]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1txd|1txd]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARHGEF12, LARG, KIAA0382 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RHOA, ARHA, ARH12, RHO12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARHGEF12, LARG, KIAA0382 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RHOA, ARHA, ARH12, RHO12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x86 OCA], [http://pdbe.org/1x86 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1x86 RCSB], [http://www.ebi.ac.uk/pdbsum/1x86 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1x86 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1x86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x86 OCA], [http://pdbe.org/1x86 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1x86 RCSB], [http://www.ebi.ac.uk/pdbsum/1x86 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1x86 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
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*[[Rho GTPase|Rho GTPase]]
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*[[Rho GTPase 3D structures|Rho GTPase 3D structures]]
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*[[Rho guanine nucleotide exchange factor|Rho guanine nucleotide exchange factor]]
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*[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
 +
[[Category: Large Structures]]
[[Category: Gao, G]]
[[Category: Gao, G]]
[[Category: Kristelly, R]]
[[Category: Kristelly, R]]
[[Category: Tesmer, J J]]
[[Category: Tesmer, J J]]
[[Category: Signaling protein-membrane protein complex]]
[[Category: Signaling protein-membrane protein complex]]

Revision as of 09:47, 6 January 2021

Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA

PDB ID 1x86

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