1xsp

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==Crystal Structure of human DNA polymerase lambda in complex with nicked DNA and pyrophosphate==
==Crystal Structure of human DNA polymerase lambda in complex with nicked DNA and pyrophosphate==
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<StructureSection load='1xsp' size='340' side='right' caption='[[1xsp]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='1xsp' size='340' side='right'caption='[[1xsp]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xsp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XSP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xsp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XSP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XSP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xsl|1xsl]], [[1xsn|1xsn]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xsl|1xsl]], [[1xsn|1xsn]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xsp OCA], [http://pdbe.org/1xsp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xsp RCSB], [http://www.ebi.ac.uk/pdbsum/1xsp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xsp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xsp OCA], [http://pdbe.org/1xsp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xsp RCSB], [http://www.ebi.ac.uk/pdbsum/1xsp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xsp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 1xsp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1xsp" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Bebenek, K]]
[[Category: Bebenek, K]]
[[Category: Garcia-Diaz, M]]
[[Category: Garcia-Diaz, M]]

Revision as of 10:18, 6 January 2021

Crystal Structure of human DNA polymerase lambda in complex with nicked DNA and pyrophosphate

PDB ID 1xsp

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