Urease accessory protein

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*'''UreF''' - modulates the activation process of urease by eliminating the binding of Ni irons to noncarbamylated protein<ref>PMID:8808930</ref>.<br />
*'''UreF''' - modulates the activation process of urease by eliminating the binding of Ni irons to noncarbamylated protein<ref>PMID:8808930</ref>.<br />
*'''UreG''' - modulates the activation process of urease in plants <ref>PMID:28710280</ref>.<br />
*'''UreG''' - modulates the activation process of urease in plants <ref>PMID:28710280</ref>.<br />
 +
*'''UreH''' - forms in combination with UreF and UreG a pre-activation complex which activates urease<ref>PMID:22013070</ref>.<br />
*'''UreI''' - probably facilitates nickel incorporation.<br />
*'''UreI''' - probably facilitates nickel incorporation.<br />
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**[[2wgl]], [[3cxn]], [[3o1q]] – HpUreF <br />
**[[2wgl]], [[3cxn]], [[3o1q]] – HpUreF <br />
**[[3sf5]] – HpUreF + HpUreH<br />
**[[3sf5]] – HpUreF + HpUreH<br />
-
**[[4hi0]] – HpUreF + HpUreG + HpUreH<br />
+
**[[4hi0]] – HpUreF + HpUreG + HpUreH + GDP<br />
**[[6jc4]] – KpUreE – ''Klebsiella pnemoniae''<br />
**[[6jc4]] – KpUreE – ''Klebsiella pnemoniae''<br />

Revision as of 09:14, 7 January 2021

Structure of UreE complex with formate and Ni+2 (PDB code 3tj8)

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3D structures of urease accessory protein

Updated on 07-January-2021

References

  1. Witte CP, Isidore E, Tiller SA, Davies HV, Taylor MA. Functional characterisation of urease accessory protein G (ureG) from potato. Plant Mol Biol. 2001 Jan;45(2):169-79. PMID:11289508
  2. Moncrief MB, Hausinger RP. Purification and activation properties of UreD-UreF-urease apoprotein complexes. J Bacteriol. 1996 Sep;178(18):5417-21. PMID:8808930
  3. Myrach T, Zhu A, Witte CP. The assembly of the plant urease activation complex and the essential role of the urease accessory protein G (UreG) in delivery of nickel to urease. J Biol Chem. 2017 Sep 1;292(35):14556-14565. doi: 10.1074/jbc.M117.780403. Epub, 2017 Jul 14. PMID:28710280 doi:http://dx.doi.org/10.1074/jbc.M117.780403
  4. Fong YH, Wong HC, Chuck CP, Chen YW, Sun H, Wong KB. Assembly of Preactivation Complex for Urease Maturation in Helicobacter pylori: CRYSTAL STRUCTURE OF UreF-UreH PROTEIN COMPLEX. J Biol Chem. 2011 Dec 16;286(50):43241-9. Epub 2011 Oct 19. PMID:22013070 doi:10.1074/jbc.M111.296830
  5. Banaszak K, Martin-Diaconescu V, Bellucci M, Zambelli B, Rypniewski W, Maroney MJ, Ciurli S. Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveal a role for the disordered C-terminal arm in metal trafficking. Biochem J. 2011 Oct 20. PMID:22010876 doi:10.1042/BJ20111659

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