User talk:Daniel Hausaman

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==Remdesivir==
== Introduction ==
== Introduction ==
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== Structural highlights ==
== Structural highlights ==
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<Structure load='7bv2' size='400' frame='true' align='right' caption='The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP)' scene='Insert optional scene name here' />
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== References

Revision as of 11:07, 12 January 2021

Contents

Remdesivir

Introduction

SARS-CoV-2 also known as severe acute respiratory syndrome coronavirus 2 or COVID-19 is a respiratory disease that is capable of progressing to viral pneumonia and can also lead to death. SARS-Cov2 relies upon RNA-dependent RNA polymerase (RdRp) to replicate the viral genetic material. Drugs such as nucleoside analogues can be used to inhibit this enzyme and stop viral replication. Remdesivir initially labeled GS-5734 is an adenosine triphosphate analogue, used as a broad-spectrum antiviral drug meaning it can be used to inhibit a wide range of viruses that rely upon RNA-dependent RNA polymerase for genomic replication.


Function

Mechanism

Disease

Relevance

Structural highlights

The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP)

Drag the structure with the mouse to rotate

== References

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