User talk:Daniel Hausaman
From Proteopedia
(Difference between revisions)
												
			
			| Line 1: | Line 1: | ||
| - | + | ==Remdesivir== | |
| == Introduction == | == Introduction == | ||
| Line 16: | Line 16: | ||
| == Structural highlights == | == Structural highlights == | ||
| + | <Structure load='7bv2' size='400' frame='true' align='right' caption='The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP)' scene='Insert optional scene name here' /> | ||
| + | == References | ||
Revision as of 11:07, 12 January 2021
| Contents | 
Remdesivir
Introduction
SARS-CoV-2 also known as severe acute respiratory syndrome coronavirus 2 or COVID-19 is a respiratory disease that is capable of progressing to viral pneumonia and can also lead to death. SARS-Cov2 relies upon RNA-dependent RNA polymerase (RdRp) to replicate the viral genetic material. Drugs such as nucleoside analogues can be used to inhibit this enzyme and stop viral replication. Remdesivir initially labeled GS-5734 is an adenosine triphosphate analogue, used as a broad-spectrum antiviral drug meaning it can be used to inhibit a wide range of viruses that rely upon RNA-dependent RNA polymerase for genomic replication.
Function
Mechanism
Disease
Relevance
Structural highlights
| 
 | 
== References
