7clt

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==mitochondrial calcium binding protein==
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==Crystal structure of the EFhd1/Swiprosin-2, a mitochondrial actin-binding protein==
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<StructureSection load='7clt' size='340' side='right'caption='[[7clt]]' scene=''>
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<StructureSection load='7clt' size='340' side='right'caption='[[7clt]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CLT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7CLT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7clt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CLT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7CLT FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7clt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7clt OCA], [http://pdbe.org/7clt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7clt RCSB], [http://www.ebi.ac.uk/pdbsum/7clt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7clt ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Efhd1, Sws2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7clt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7clt OCA], [http://pdbe.org/7clt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7clt RCSB], [http://www.ebi.ac.uk/pdbsum/7clt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7clt ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/EFHD1_MOUSE EFHD1_MOUSE]] Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production (By similarity). May play a role in neuronal differentiation (PubMed:16336229).[UniProtKB:Q9BUP0]<ref>PMID:16336229</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Eom SH]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Jin M]]
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[[Category: Eom, S H]]
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[[Category: Jun CD]]
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[[Category: Jin, M]]
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[[Category: Kang JY]]
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[[Category: Jun, C D]]
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[[Category: Lee Y]]
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[[Category: Kang, J Y]]
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[[Category: Mun SA]]
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[[Category: Lee, Y]]
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[[Category: Park J]]
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[[Category: Mun, S A]]
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[[Category: Park KR]]
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[[Category: Park, J]]
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[[Category: Park T]]
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[[Category: Park, K R]]
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[[Category: Yang J]]
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[[Category: Park, T]]
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[[Category: Yang, J]]
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[[Category: Calcium-binding]]
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[[Category: Metal binding protein]]
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[[Category: Mitochondria]]

Revision as of 06:04, 20 January 2021

Crystal structure of the EFhd1/Swiprosin-2, a mitochondrial actin-binding protein

PDB ID 7clt

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