This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1zrj
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Solution structure of the SAP domain of human E1B-55kDa-associated protein 5 isoform c== | ==Solution structure of the SAP domain of human E1B-55kDa-associated protein 5 isoform c== | ||
| - | <StructureSection load='1zrj' size='340' side='right' caption='[[1zrj]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='1zrj' size='340' side='right'caption='[[1zrj]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1zrj]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1zrj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZRJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZRJ FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNRPUL1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNRPUL1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zrj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zrj OCA], [https://pdbe.org/1zrj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zrj RCSB], [https://www.ebi.ac.uk/pdbsum/1zrj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zrj ProSAT], [https://www.topsan.org/Proteins/RSGI/1zrj TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HNRL1_HUMAN HNRL1_HUMAN]] Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.<ref>PMID:9733834</ref> <ref>PMID:12489984</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 24: | Line 24: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
[[Category: Kigawa, T]] | [[Category: Kigawa, T]] | ||
Revision as of 08:15, 27 January 2021
Solution structure of the SAP domain of human E1B-55kDa-associated protein 5 isoform c
| |||||||||||
