2a55

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain.==
==Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain.==
-
<StructureSection load='2a55' size='340' side='right' caption='[[2a55]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
+
<StructureSection load='2a55' size='340' side='right'caption='[[2a55]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2a55]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A55 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A55 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2a55]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A55 FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C4BPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C4BPA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a55 OCA], [http://pdbe.org/2a55 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2a55 RCSB], [http://www.ebi.ac.uk/pdbsum/2a55 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2a55 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a55 OCA], [https://pdbe.org/2a55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a55 RCSB], [https://www.ebi.ac.uk/pdbsum/2a55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a55 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/C4BPA_HUMAN C4BPA_HUMAN]] Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
+
[[https://www.uniprot.org/uniprot/C4BPA_HUMAN C4BPA_HUMAN]] Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 33: Line 33:
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
 +
[[Category: Large Structures]]
[[Category: Ball, G]]
[[Category: Ball, G]]
[[Category: Barlow, P N]]
[[Category: Barlow, P N]]

Revision as of 08:25, 27 January 2021

Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain.

PDB ID 2a55

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2a55"
Personal tools