2am3
From Proteopedia
(Difference between revisions)
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==Crystal Structure of N-Acetylglucosaminyltransferase I in Complex with UDP-Glucose== | ==Crystal Structure of N-Acetylglucosaminyltransferase I in Complex with UDP-Glucose== | ||
- | <StructureSection load='2am3' size='340' side='right' caption='[[2am3]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='2am3' size='340' side='right'caption='[[2am3]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2am3]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2am3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/European_rabbit European rabbit]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AM3 FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr> |
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1foa|1foa]], [[1fo9|1fo9]], [[1fo8|1fo8]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1foa|1foa]], [[1fo9|1fo9]], [[1fo8|1fo8]]</div></td></tr> |
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MGAT1, GNT1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MGAT1, GNT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9986 European rabbit])</td></tr> |
- | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alpha-1,3-mannosyl-glycoprotein_2-beta-N-acetylglucosaminyltransferase Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.101 2.4.1.101] </span></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2am3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2am3 OCA], [https://pdbe.org/2am3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2am3 RCSB], [https://www.ebi.ac.uk/pdbsum/2am3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2am3 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/MGAT1_RABIT MGAT1_RABIT]] Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
- | *[[O-GlcNAc transferase|O-GlcNAc transferase]] | + | *[[O-GlcNAc transferase 3D structures|O-GlcNAc transferase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase]] | [[Category: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase]] | ||
[[Category: European rabbit]] | [[Category: European rabbit]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Gordon, R D]] | [[Category: Gordon, R D]] | ||
[[Category: Rini, J M]] | [[Category: Rini, J M]] |
Revision as of 08:33, 27 January 2021
Crystal Structure of N-Acetylglucosaminyltransferase I in Complex with UDP-Glucose
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