TRAP dicarboxylate transporter, DctP subunit
From Proteopedia
(Difference between revisions)
| Line 6: | Line 6: | ||
== Disease == | == Disease == | ||
| - | |||
| - | RPE1 has been shown to mitigate host cell defenses leading to the development of cancer induces apoptosis of its host cells<ref>PMID:29495005</ref>. | ||
==Relevance== | ==Relevance== | ||
| - | |||
| - | The detection of RPE1 mRNA and promoter methylation may serve as cancer prognostic marker. | ||
== Structural highlights == | == Structural highlights == | ||
| - | The complex between BPV1 DBD and 21-bp DNA (PDB code [[1ksx]]) shows 2 DBD-DNA binding modules: a binding loop and a binding helix each interacting with a single strand. The protein-DNA interactions are hydrophilic to phosphate atoms and van der Waals hydrophobic ones<ref>PMID:11889054</ref>. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of TRAP dicarboxylate transporter, DctP subunit== | ==3D structures of TRAP dicarboxylate transporter, DctP subunit== | ||
Current revision
| |||||||||||
3D structures of TRAP dicarboxylate transporter, DctP subunit
Updated on 01-February-2021
References
- ↑ Rabus R, Jack DL, Kelly DJ, Saier MH Jr. TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters. Microbiology (Reading). 1999 Dec;145 ( Pt 12):3431-3445. doi:, 10.1099/00221287-145-12-3431. PMID:10627041 doi:http://dx.doi.org/10.1099/00221287-145-12-3431
