Chalcone synthase

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==Function==
==Function==
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'''Chalcone synthase''' is part of the tripartite ATP-dependent transporters which consist of three protiens: DctP, DctM and DctQ. DctP is a periplasmic C4-dicarboxylate-binding receptor<ref>PMID:10627041</ref>.
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'''Chalcone synthase''' (CHS) is essential for the biosynthesis of flavonoids and anthocyanin pigments in plants. CHS condenses p-coumaroyl-CoA and three malonyl-CoA to produce naringenin
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<ref>PMID:25404490</ref>.
== Disease ==
== Disease ==
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*Chalcone synthase
*Chalcone synthase
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**[[1bi5]], [[1u0v]] - alCS 2 - alfalfa<br />
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**[[1bi5]], [[1u0v]] - alCHS 2 - alfalfa<br />
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**[[1d6f]], [[1d6i]], [[1i86]], [[1i88]], [[1i89]], [[1i8b]], [[1jwx]] - alCS 2 (mutant)<br />
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**[[1d6f]], [[1d6i]], [[1i86]], [[1i88]], [[1i89]], [[1i8b]], [[1jwx]] - alCHS 2 (mutant)<br />
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**[[6dxb]] - AtCS - ''Arabidopsis thaliana''<br />
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**[[6dxb]] - AtCHS - ''Arabidopsis thaliana''<br />
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**[[6dxd]], [[6dxe]] - AtCS (mutant) <br />
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**[[6dxd]], [[6dxe]] - AtCHS (mutant) <br />
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**[[4wum]] - CS - freesia<br />
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**[[4wum]] - CHS - freesia<br />
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**[[6dxa]] - CS - pine<br />
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**[[6dxa]] - CHS - pine<br />
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**[[6dx9]] - CS - horsetail<br />
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**[[6dx9]] - CHS - horsetail<br />
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**[[7bus]] - sbCS - soybean<br />
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**[[7bus]] - sbCHS - soybean<br />
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**[[7dx7]] - CS - moss<br />
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**[[7dx7]] - CHS - moss<br />
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**[[5uc5]] - CS - apple<br />
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**[[5uc5]] - CHS - apple<br />
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**[[4yjy]] - CS 1 - rice<br />
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**[[4yjy]] - CHS 1 - rice<br />
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**[[6dx8]], [[6dxc]], [[6dxf]] - CS - ''Selaginella moellendorffii''<br />
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**[[6dx8]], [[6dxc]], [[6dxf]] - CHS - ''Selaginella moellendorffii''<br />
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**[[6cqb]] - CS - kava<br />
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**[[6cqb]] - CHS - kava<br />
*Chalcone synthase complex
*Chalcone synthase complex
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**[[1cgk]] - alCS + naringenin<br />
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**[[1cgk]] - alCHS + naringenin<br />
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**[[1cgz]] - alCS + resveratol<br />
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**[[1cgz]] - alCHS + resveratol<br />
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**[[1u0w]] - alCS 2 (mutant) + resveratol<br />
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**[[1u0w]] - alCHS 2 (mutant) + resveratol<br />
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**[[1bq6]] - alCS + CoA<br />
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**[[1bq6]] - alCHS + CoA<br />
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**[[1d6h]] - alCS (mutant) + CoA<br />
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**[[1d6h]] - alCHS (mutant) + CoA<br />
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**[[1cml]] - alCS + malonyl-CoA<br />
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**[[1cml]] - alCHS + malonyl-CoA<br />
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**[[1chw]] - alCS (mutant) + hexanoyl-CoA<br />
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**[[1chw]] - alCHS (mutant) + hexanoyl-CoA<br />
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**[[7bur]] - sbCS + naringenin<br />
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**[[7bur]] - sbCHS + naringenin<br />
}}
}}

Revision as of 09:31, 1 February 2021

DctP complex with glucuronate (PDB code 4mhf)

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Chalcone synthase

Updated on 01-February-2021

References

  1. ↑ Yu HN, Wang L, Sun B, Gao S, Cheng AX, Lou HX. Functional characterization of a chalcone synthase from the liverwort Plagiochasma appendiculatum. Plant Cell Rep. 2015 Feb;34(2):233-45. doi: 10.1007/s00299-014-1702-8. Epub 2014 , Nov 18. PMID:25404490 doi:http://dx.doi.org/10.1007/s00299-014-1702-8

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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