2bay
From Proteopedia
(Difference between revisions)
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==Crystal structure of the Prp19 U-box dimer== | ==Crystal structure of the Prp19 U-box dimer== | ||
- | <StructureSection load='2bay' size='340' side='right' caption='[[2bay]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='2bay' size='340' side='right'caption='[[2bay]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2bay]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2bay]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BAY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BAY FirstGlance]. <br> |
- | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRP19, PSO4 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRP19, PSO4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bay FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bay OCA], [https://pdbe.org/2bay PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bay RCSB], [https://www.ebi.ac.uk/pdbsum/2bay PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bay ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/PRP19_YEAST PRP19_YEAST]] Involved in pre-mRNA splicing. Acts a central component of the NTC complex (or PRP19-associated complex) that associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. Involved in DNA repair. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
- | *[[Pre-mRNA | + | *[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Atcc 18824]] | [[Category: Atcc 18824]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Chazin, W J]] | [[Category: Chazin, W J]] | ||
[[Category: Gould, K L]] | [[Category: Gould, K L]] |
Revision as of 11:39, 3 February 2021
Crystal structure of the Prp19 U-box dimer
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Categories: Atcc 18824 | Large Structures | Chazin, W J | Gould, K L | Kooi, C W.Vander | Newcomer, M E | Ohi, M D | Oldham, M L | Rosenberg, J A | E3 ligase | Ligase | Prp19 | U-box | Ubiquitin ligase