2chx

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==A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-90==
==A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-90==
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<StructureSection load='2chx' size='340' side='right' caption='[[2chx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='2chx' size='340' side='right'caption='[[2chx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2chx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2chx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=090:N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C]+QUINAZOLIN-5-YL)NICOTINAMIDE'>090</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=090:N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C]+QUINAZOLIN-5-YL)NICOTINAMIDE'>090</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e8y|1e8y]], [[1e8z|1e8z]], [[1he8|1he8]], [[2a4z|2a4z]], [[2a5u|2a5u]], [[2chw|2chw]], [[2chz|2chz]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1e8y|1e8y]], [[1e8z|1e8z]], [[1he8|1he8]], [[2a4z|2a4z]], [[2a5u|2a5u]], [[2chw|2chw]], [[2chz|2chz]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chx OCA], [http://pdbe.org/2chx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chx RCSB], [http://www.ebi.ac.uk/pdbsum/2chx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2chx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chx OCA], [https://pdbe.org/2chx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chx RCSB], [https://www.ebi.ac.uk/pdbsum/2chx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chx ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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==See Also==
==See Also==
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*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]
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*[[Phosphoinositide 3-kinase 3D structures|Phosphoinositide 3-kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Balla, A]]
[[Category: Balla, A]]
[[Category: Balla, T]]
[[Category: Balla, T]]

Revision as of 11:43, 3 February 2021

A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-90

PDB ID 2chx

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