2d9t
From Proteopedia
(Difference between revisions)
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==Solution structure of the Tudor domain of Tudor domain containing protein 3 from mouse== | ==Solution structure of the Tudor domain of Tudor domain containing protein 3 from mouse== | ||
| - | <StructureSection load='2d9t' size='340' side='right' caption='[[2d9t]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2d9t' size='340' side='right'caption='[[2d9t]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2d9t]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2d9t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D9T FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tdrd3 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tdrd3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d9t OCA], [https://pdbe.org/2d9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d9t RCSB], [https://www.ebi.ac.uk/pdbsum/2d9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d9t ProSAT], [https://www.topsan.org/Proteins/RSGI/2d9t TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TDRD3_MOUSE TDRD3_MOUSE]] Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
Revision as of 11:57, 3 February 2021
Solution structure of the Tudor domain of Tudor domain containing protein 3 from mouse
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