This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2day
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Solution structure of the RWD domain of human ring finger protein 25== | ==Solution structure of the RWD domain of human ring finger protein 25== | ||
| - | <StructureSection load='2day' size='340' side='right' caption='[[2day]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2day' size='340' side='right'caption='[[2day]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2day]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2day]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DAY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DAY FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNF25 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNF25 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2day FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2day OCA], [https://pdbe.org/2day PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2day RCSB], [https://www.ebi.ac.uk/pdbsum/2day PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2day ProSAT], [https://www.topsan.org/Proteins/RSGI/2day TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/RNF25_HUMAN RNF25_HUMAN]] E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2 (By similarity). Stimulates transcription mediated by NF-kappa-B.<ref>PMID:12748188</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 24: | Line 24: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
[[Category: Kigawa, T]] | [[Category: Kigawa, T]] | ||
Revision as of 11:58, 3 February 2021
Solution structure of the RWD domain of human ring finger protein 25
| |||||||||||
Categories: Human | Large Structures | Inoue, M | Kigawa, T | Koshiba, S | Structural genomic | Sato, M | Tochio, N | Yokoyama, S | Yoneyama, M | Alpha+beta sandwich fold | Ligase | Metal-binding | National project on protein structural and functional analyse | Nppsfa | Rsgi | Rwd domain | Ub1 conjugation | Ub1 conjugation pathway
