2dms
From Proteopedia
(Difference between revisions)
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==Solution structure of the homeobox domain of Homeobox protein OTX2== | ==Solution structure of the homeobox domain of Homeobox protein OTX2== | ||
| - | <StructureSection load='2dms' size='340' side='right' caption='[[2dms]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2dms' size='340' side='right'caption='[[2dms]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dms]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dms]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMS FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Otx2 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Otx2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dms OCA], [https://pdbe.org/2dms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dms RCSB], [https://www.ebi.ac.uk/pdbsum/2dms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dms ProSAT], [https://www.topsan.org/Proteins/RSGI/2dms TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/OTX2_MOUSE OTX2_MOUSE]] Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
Revision as of 12:08, 3 February 2021
Solution structure of the homeobox domain of Homeobox protein OTX2
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Categories: Large Structures | Lk3 transgenic mice | Inoue, M | Kigawa, T | Koshiba, S | Ohnishi, S | Structural genomic | Saito, K | Yokoyama, S | Dna binding protein | Homeobox domain | National project on protein structural and functional analyse | Nppsfa | Rsgi | Three helices with the dna binding helix-turn-helix motif
