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2duo

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==Crystal structure of VIP36 exoplasmic/lumenal domain, Ca2+-bound form==
==Crystal structure of VIP36 exoplasmic/lumenal domain, Ca2+-bound form==
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<StructureSection load='2duo' size='340' side='right' caption='[[2duo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='2duo' size='340' side='right'caption='[[2duo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2duo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Canlf Canlf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DUO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2duo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Canlf Canlf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DUO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gv9|1gv9]], [[1r1z|1r1z]], [[2dup|2dup]], [[2duq|2duq]], [[2dur|2dur]], [[2dus|2dus]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gv9|1gv9]], [[1r1z|1r1z]], [[2dup|2dup]], [[2duq|2duq]], [[2dur|2dur]], [[2dus|2dus]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMAN2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMAN2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2duo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2duo OCA], [http://pdbe.org/2duo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2duo RCSB], [http://www.ebi.ac.uk/pdbsum/2duo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2duo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2duo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2duo OCA], [https://pdbe.org/2duo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2duo RCSB], [https://www.ebi.ac.uk/pdbsum/2duo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2duo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LMAN2_CANFA LMAN2_CANFA]] Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans.<ref>PMID:11872745</ref> <ref>PMID:17652092</ref>
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[[https://www.uniprot.org/uniprot/LMAN2_CANFA LMAN2_CANFA]] Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans.<ref>PMID:11872745</ref> <ref>PMID:17652092</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Canlf]]
[[Category: Canlf]]
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[[Category: Large Structures]]
[[Category: Cowieson, N P]]
[[Category: Cowieson, N P]]
[[Category: Kato, R]]
[[Category: Kato, R]]

Revision as of 11:38, 10 February 2021

Crystal structure of VIP36 exoplasmic/lumenal domain, Ca2+-bound form

PDB ID 2duo

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