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2duo
From Proteopedia
(Difference between revisions)
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==Crystal structure of VIP36 exoplasmic/lumenal domain, Ca2+-bound form== | ==Crystal structure of VIP36 exoplasmic/lumenal domain, Ca2+-bound form== | ||
| - | <StructureSection load='2duo' size='340' side='right' caption='[[2duo]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='2duo' size='340' side='right'caption='[[2duo]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2duo]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2duo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Canlf Canlf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DUO FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gv9|1gv9]], [[1r1z|1r1z]], [[2dup|2dup]], [[2duq|2duq]], [[2dur|2dur]], [[2dus|2dus]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gv9|1gv9]], [[1r1z|1r1z]], [[2dup|2dup]], [[2duq|2duq]], [[2dur|2dur]], [[2dus|2dus]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMAN2 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMAN2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2duo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2duo OCA], [https://pdbe.org/2duo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2duo RCSB], [https://www.ebi.ac.uk/pdbsum/2duo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2duo ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/LMAN2_CANFA LMAN2_CANFA]] Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans.<ref>PMID:11872745</ref> <ref>PMID:17652092</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Canlf]] | [[Category: Canlf]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Cowieson, N P]] | [[Category: Cowieson, N P]] | ||
[[Category: Kato, R]] | [[Category: Kato, R]] | ||
Revision as of 11:38, 10 February 2021
Crystal structure of VIP36 exoplasmic/lumenal domain, Ca2+-bound form
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