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2dyu
From Proteopedia
(Difference between revisions)
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==Helicobacter pylori formamidase AmiF contains a fine-tuned cysteine-glutamate-lysine catalytic triad== | ==Helicobacter pylori formamidase AmiF contains a fine-tuned cysteine-glutamate-lysine catalytic triad== | ||
| - | <StructureSection load='2dyu' size='340' side='right' caption='[[2dyu]], [[Resolution|resolution]] 1.75Å' scene=''> | + | <StructureSection load='2dyu' size='340' side='right'caption='[[2dyu]], [[Resolution|resolution]] 1.75Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dyu]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dyu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYU FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dyv|2dyv]], [[2e2k|2e2k]], [[2e2l|2e2l]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dyv|2dyv]], [[2e2k|2e2k]], [[2e2l|2e2l]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">amiF ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">amiF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85962 Campylobacter pylori])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Formamidase Formamidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.49 3.5.1.49] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyu OCA], [https://pdbe.org/2dyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyu RCSB], [https://www.ebi.ac.uk/pdbsum/2dyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyu ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/AMIF_HELPY AMIF_HELPY]] Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide. Probably involved in the nitrogen metabolism of H.pylori.<ref>PMID:11359566</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Campylobacter pylori]] | [[Category: Campylobacter pylori]] | ||
[[Category: Formamidase]] | [[Category: Formamidase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hung, C L]] | [[Category: Hung, C L]] | ||
[[Category: Wang, W C]] | [[Category: Wang, W C]] | ||
Revision as of 11:41, 10 February 2021
Helicobacter pylori formamidase AmiF contains a fine-tuned cysteine-glutamate-lysine catalytic triad
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