2efj

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==The structure of 1,7 dimethylxanthine methyltransferase==
==The structure of 1,7 dimethylxanthine methyltransferase==
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<StructureSection load='2efj' size='340' side='right' caption='[[2efj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2efj' size='340' side='right'caption='[[2efj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2efj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cofca Cofca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EFJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2efj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cofca Cofca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EFJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=37T:THEOBROMINE'>37T</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=37T:THEOBROMINE'>37T</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2eg5|2eg5]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2eg5|2eg5]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DXMT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=49390 COFCA])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DXMT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=49390 COFCA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efj OCA], [http://pdbe.org/2efj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2efj RCSB], [http://www.ebi.ac.uk/pdbsum/2efj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2efj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2efj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efj OCA], [https://pdbe.org/2efj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2efj RCSB], [https://www.ebi.ac.uk/pdbsum/2efj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2efj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DXMT1_COFCA DXMT1_COFCA]] Involved in the biosynthesis of caffeine. Catalyzes the conversion of 7-methylxanthine to theobromine and of theobromine to caffeine, but no sequential conversion of 7-methylxanthine to caffeine was detected.
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[[https://www.uniprot.org/uniprot/DXMT1_COFCA DXMT1_COFCA]] Involved in the biosynthesis of caffeine. Catalyzes the conversion of 7-methylxanthine to theobromine and of theobromine to caffeine, but no sequential conversion of 7-methylxanthine to caffeine was detected.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Cofca]]
[[Category: Cofca]]
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[[Category: Large Structures]]
[[Category: McCarthy, A A]]
[[Category: McCarthy, A A]]
[[Category: McCarthy, J G]]
[[Category: McCarthy, J G]]

Revision as of 12:04, 10 February 2021

The structure of 1,7 dimethylxanthine methyltransferase

PDB ID 2efj

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