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2eqn

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==Solution structure of the NAF1 domain of Hypothetical protein BC008207 [Homo sapiens]==
==Solution structure of the NAF1 domain of Hypothetical protein BC008207 [Homo sapiens]==
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<StructureSection load='2eqn' size='340' side='right' caption='[[2eqn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2eqn' size='340' side='right'caption='[[2eqn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2eqn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EQN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2eqn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQN FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LOC92345 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LOC92345 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqn OCA], [http://pdbe.org/2eqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eqn RCSB], [http://www.ebi.ac.uk/pdbsum/2eqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqn ProSAT], [http://www.topsan.org/Proteins/RSGI/2eqn TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqn OCA], [https://pdbe.org/2eqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqn RCSB], [https://www.ebi.ac.uk/pdbsum/2eqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqn ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqn TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NAF1_HUMAN NAF1_HUMAN]] RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.<ref>PMID:16618814</ref>
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[[https://www.uniprot.org/uniprot/NAF1_HUMAN NAF1_HUMAN]] RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.<ref>PMID:16618814</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Dang, W]]
[[Category: Dang, W]]
[[Category: Inoue, M]]
[[Category: Inoue, M]]

Revision as of 12:25, 10 February 2021

Solution structure of the NAF1 domain of Hypothetical protein BC008207 [Homo sapiens]

PDB ID 2eqn

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