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2ey4
From Proteopedia
(Difference between revisions)
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==Crystal Structure of a Cbf5-Nop10-Gar1 Complex== | ==Crystal Structure of a Cbf5-Nop10-Gar1 Complex== | ||
| - | <StructureSection load='2ey4' size='340' side='right' caption='[[2ey4]], [[Resolution|resolution]] 2.11Å' scene=''> | + | <StructureSection load='2ey4' size='340' side='right'caption='[[2ey4]], [[Resolution|resolution]] 2.11Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ey4]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ey4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587] and [https://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EY4 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">truB ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">truB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ey4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ey4 OCA], [https://pdbe.org/2ey4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ey4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ey4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ey4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TRUB_PYRFU TRUB_PYRFU]] Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity). [[https://www.uniprot.org/uniprot/NOP10_PYRFU NOP10_PYRFU]] Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ey/2ey4_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ey/2ey4_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2ey4" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2ey4" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Guide-independent Pseudouridine synthase|Guide-independent Pseudouridine synthase]] | ||
| + | *[[Pseudouridine synthase 3D structures|Pseudouridine synthase 3D structures]] | ||
| + | *[[RNA-guided pseudouridine synthase|RNA-guided pseudouridine synthase]] | ||
| + | *[[Ribosome biogenesis protein|Ribosome biogenesis protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Atcc 43587]] | [[Category: Atcc 43587]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Pyrfu]] | [[Category: Pyrfu]] | ||
[[Category: Li, H]] | [[Category: Li, H]] | ||
Revision as of 12:34, 10 February 2021
Crystal Structure of a Cbf5-Nop10-Gar1 Complex
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