Polyhedrin

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== Structural highlights ==
== Structural highlights ==
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The biological assembly of ''Uranotaenia sapphirina'' cypovirus Polyhedrin is <scene name='87/873252/Cv/2'>homotrimer</scene> (PDB code [[4s1k]]). Nucleoside triphosphates stabilize polyhedrin by forming hydrogen bonds with Ser and Arg side chains of 2 monomers<ref>PMID:25751308</ref>.
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The biological assembly of ''Uranotaenia sapphirina'' cypovirus Polyhedrin is <scene name='87/873252/Cv/2'>homotrimer</scene> (PDB code [[4s1k]]). <scene name='87/873252/Cv/9'>ATP binding site</scene><ref>PMID:25751308</ref>. Water molecules are shown as red spheres. <scene name='87/873252/Cv/10'>Mg coordination site</scene>.
</StructureSection>
</StructureSection>

Revision as of 12:53, 10 February 2021

Polyhedrin complex with ATP (PDB code 4s1k)

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3D structures of polyhedrin

Updated on 10-February-2021

3jvb – PH – wiseana signata nucleopolyhedrovirus
2wux, 2wuy, 3jw6 – PH – autographa californica nucleopolyhedrovirus
4s1k, 4s1l, 4zqx – PH + ATP – uranotaenia sapphirina cypovirus
5a99 – obcvPH + ATP – operophtera brumata cypovirus
4ots, 4otv, 4x35, 5a9p, 5mqw – obcvPH + ATP + GTP
5gqk, 5yha, 5yhb – bmcvPH – bombyx mori cypovirus
5a9b, 5gqi, 5gqj, 5gqn, 5yr1, 5yr9, 5yra, 5yrb, 5yrc, 5yrd, 6lee – bmcvPH (mutant)
5axv – bmcvPH (mutant) + CTP
5gql – bmcvPH + ATP + CTP
5axu – bmcvPH (mutant) + ATP + CTP
2oh5, 2oh6, 2oh7, 5exy, 5exz, 5gqm – bmcvPH + ATP + GTP + CTP
5a96 – PH + GTP – lymantria dispar cypovirus
5a8s, 5a8t, 5a9c – PH (mutant) – antheraea mylitta cypovirus
5a98 – PH + ATP – trichoplusia ni cypovirus
5a9a – PH + UTP – simullium ubuquitum cypovirus
5a8u, 5a8v – PH – orgyia pseudotsugata cypovirus
5g3x – PH – cydia pomonella granulovirus

References

  1. ↑ Rohrmann GF. Polyhedrin structure. J Gen Virol. 1986 Aug;67 ( Pt 8):1499-513. doi: 10.1099/0022-1317-67-8-1499. PMID:3525744 doi:http://dx.doi.org/10.1099/0022-1317-67-8-1499
  2. ↑ Kunimi Y. Current status and prospects on microbial control in Japan. J Invertebr Pathol. 2007 Jul;95(3):181-6. doi: 10.1016/j.jip.2007.03.007. Epub, 2007 Mar 25. PMID:17462666 doi:http://dx.doi.org/10.1016/j.jip.2007.03.007
  3. ↑ Ginn HM, Messerschmidt M, Ji X, Zhang H, Axford D, Gildea RJ, Winter G, Brewster AS, Hattne J, Wagner A, Grimes JM, Evans G, Sauter NK, Sutton G, Stuart DI. Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data. Nat Commun. 2015 Mar 9;6:6435. doi: 10.1038/ncomms7435. PMID:25751308 doi:http://dx.doi.org/10.1038/ncomms7435

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Alexander Berchansky, Michal Harel

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