1dpl

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[[Image:1dpl.gif|left|200px]]
[[Image:1dpl.gif|left|200px]]
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{{Structure
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|PDB= 1dpl |SIZE=350|CAPTION= <scene name='initialview01'>1dpl</scene>, resolution 0.83&Aring;
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The line below this paragraph, containing "STRUCTURE_1dpl", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=T23:2&#39;-O-METHYL-3&#39;-METHYL-3&#39;-DEOXY-ARABINOFURANOSYL-THYMINE-5&#39;-PHOSPHATE'>T23</scene>
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|ACTIVITY=
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1dpl| PDB=1dpl | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpl OCA], [http://www.ebi.ac.uk/pdbsum/1dpl PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dpl RCSB]</span>
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}}
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'''A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE'''
'''A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE'''
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==About this Structure==
==About this Structure==
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1DPL is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA].
==Reference==
==Reference==
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10699842 10699842]
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10699842 10699842]
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[[Category: Protein complex]]
 
[[Category: An, H.]]
[[Category: An, H.]]
[[Category: Cook, P Dan.]]
[[Category: Cook, P Dan.]]
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[[Category: Tereshko, V.]]
[[Category: Tereshko, V.]]
[[Category: Weeks, C M.]]
[[Category: Weeks, C M.]]
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[[Category: deoxyribonucleic acid]]
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[[Category: Deoxyribonucleic acid]]
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[[Category: modified a-decamer at 0 83 a resolution]]
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[[Category: Modified a-decamer at 0 83 a resolution]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:07:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:46:11 2008''
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Revision as of 11:07, 2 May 2008

Image:1dpl.gif

Template:STRUCTURE 1dpl

A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE


Overview

We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.

About this Structure

Full crystallographic information is available from OCA.

Reference

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:10699842 Page seeded by OCA on Fri May 2 14:07:14 2008

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