1dps

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1dps.jpg|left|200px]]
[[Image:1dps.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1dps |SIZE=350|CAPTION= <scene name='initialview01'>1dps</scene>, resolution 1.60&Aring;
+
The line below this paragraph, containing "STRUCTURE_1dps", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= DPS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1dps| PDB=1dps | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dps OCA], [http://www.ebi.ac.uk/pdbsum/1dps PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dps RCSB]</span>
+
-
}}
+
'''THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA'''
'''THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA'''
Line 30: Line 27:
[[Category: Hogle, J M.]]
[[Category: Hogle, J M.]]
[[Category: Kolter, R.]]
[[Category: Kolter, R.]]
-
[[Category: dna-binding protein]]
+
[[Category: Dna-binding protein]]
-
[[Category: ferritin]]
+
[[Category: Ferritin]]
-
[[Category: iron sequestration]]
+
[[Category: Iron sequestration]]
-
[[Category: oxidative damage]]
+
[[Category: Oxidative damage]]
-
[[Category: stationary phase]]
+
[[Category: Stationary phase]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:07:46 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:46:17 2008''
+

Revision as of 11:07, 2 May 2008

Image:1dps.jpg

Template:STRUCTURE 1dps

THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA


Overview

The crystal structure of Dps, a DNA-binding protein from starved E. coli that protects DNA from oxidative damage, has been solved at 1.6 A resolution. The Dps monomer has essentially the same fold as ferritin, which forms a 24-mer with 432 symmetry, a hollow core and pores at the three-fold axes. Dps forms a dodecamer with 23 (tetrahedral) point group symmetry which also has a hollow core and pores at the three-folds. The structure suggests a novel DNA-binding motif and a mechanism for DNA protection based on the sequestration of Fe ions.

About this Structure

1DPS is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The crystal structure of Dps, a ferritin homolog that binds and protects DNA., Grant RA, Filman DJ, Finkel SE, Kolter R, Hogle JM, Nat Struct Biol. 1998 Apr;5(4):294-303. PMID:9546221 Page seeded by OCA on Fri May 2 14:07:46 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1dps"
Personal tools