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1aoj

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<StructureSection load='1aoj' size='340' side='right'caption='[[1aoj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1aoj' size='340' side='right'caption='[[1aoj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1aoj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AOJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1AOJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1aoj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AOJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AOJ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aoj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aoj OCA], [http://pdbe.org/1aoj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1aoj RCSB], [http://www.ebi.ac.uk/pdbsum/1aoj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1aoj ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aoj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aoj OCA], [https://pdbe.org/1aoj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aoj RCSB], [https://www.ebi.ac.uk/pdbsum/1aoj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aoj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EPS8_MOUSE EPS8_MOUSE]] Upon binding to EGF receptor/EGFR enhances EGF-dependent mitogenic signals. Can bind multiple cellular targets.<ref>PMID:8404850</ref>
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[[https://www.uniprot.org/uniprot/EPS8_MOUSE EPS8_MOUSE]] Upon binding to EGF receptor/EGFR enhances EGF-dependent mitogenic signals. Can bind multiple cellular targets.<ref>PMID:8404850</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 10:22, 17 February 2021

THE SH3 DOMAIN OF EPS8 EXISTS AS A NOVEL INTERTWINED DIMER

PDB ID 1aoj

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