2fgt

From Proteopedia

(Difference between revisions)

Revision as of 07:17, 24 February 2021

Crystal Structure of YycH from Bacillus subtilis

Structural highlights

2fgt is a 1 chain structure with sequence from "bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:	yycH ("Bacillus globigii" Migula 1900)
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[YYCH_BACSU] Together with YycI, regulates the activity of the two-component system YycF/YycG.^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The Bacillus subtilis YycFG two-component signal transduction system is essential for cell viability, and the YycH protein is part of the regulatory circuit that controls its activity. The crystal structure of YycH was solved by two-wavelength selenium anomalous dispersion data, and was refined using 2.3 A data to an R-factor of 25.2%. The molecule is made up of three domains, and has a novel three-dimensional structure. The N-terminal domain features a calcium binding site and the central domain contains two conserved loop regions.

The crystal structure of YycH involved in the regulation of the essential YycFG two-component system in Bacillus subtilis reveals a novel tertiary structure.,Szurmant H, Zhao H, Mohan MA, Hoch JA, Varughese KI Protein Sci. 2006 Apr;15(4):929-34. PMID:16600972^[3]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Szurmant H, Mohan MA, Imus PM, Hoch JA. YycH and YycI interact to regulate the essential YycFG two-component system in Bacillus subtilis. J Bacteriol. 2007 Apr;189(8):3280-9. Epub 2007 Feb 16. PMID:17307850 doi:http://dx.doi.org/10.1128/JB.01936-06
↑ Szurmant H, Bu L, Brooks CL 3rd, Hoch JA. An essential sensor histidine kinase controlled by transmembrane helix interactions with its auxiliary proteins. Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5891-6. doi:, 10.1073/pnas.0800247105. Epub 2008 Apr 11. PMID:18408157 doi:http://dx.doi.org/10.1073/pnas.0800247105
↑ Szurmant H, Zhao H, Mohan MA, Hoch JA, Varughese KI. The crystal structure of YycH involved in the regulation of the essential YycFG two-component system in Bacillus subtilis reveals a novel tertiary structure. Protein Sci. 2006 Apr;15(4):929-34. PMID:16600972 doi:15/4/929

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2fgt"

@@ Line 1: / Line 1: @@
 ==Crystal Structure of YycH from Bacillus subtilis==
-<StructureSection load='2fgt' size='340' side='right' caption='[[2fgt]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+<StructureSection load='2fgt' size='340' side='right'caption='[[2fgt]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2fgt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FGT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FGT FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2fgt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FGT FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yycH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yycH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fgt OCA], [http://pdbe.org/2fgt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fgt RCSB], [http://www.ebi.ac.uk/pdbsum/2fgt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fgt ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fgt OCA], [https://pdbe.org/2fgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fgt RCSB], [https://www.ebi.ac.uk/pdbsum/2fgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fgt ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/YYCH_BACSU YYCH_BACSU]] Together with YycI, regulates the activity of the two-component system YycF/YycG.<ref>PMID:17307850</ref> <ref>PMID:18408157</ref>
+[[https://www.uniprot.org/uniprot/YYCH_BACSU YYCH_BACSU]] Together with YycI, regulates the activity of the two-component system YycF/YycG.<ref>PMID:17307850</ref> <ref>PMID:18408157</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
   <jmolCheckbox>
-    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fg/2fgt_consurf.spt"</scriptWhenChecked>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fg/2fgt_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 33: / Line 33: @@
 </StructureSection>
 [[Category: Bacillus globigii migula 1900]]
+[[Category: Large Structures]]
 [[Category: James, H A]]
 [[Category: Mohan, M A]]

2fgt

From Proteopedia

Revision as of 07:17, 24 February 2021

Crystal Structure of YycH from Bacillus subtilis

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox