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1qdb

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Revision as of 14:49, 3 March 2021

CYTOCHROME C NITRITE REDUCTASE

Structural highlights

1qdb is a 3 chain structure with sequence from Sulfurospirillum deleyianum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NRFA_SULDE] Plays a role in nitrite reduction.[HAMAP-Rule:MF_01182]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The enzyme cytochrome c nitrite reductase catalyses the six-electron reduction of nitrite to ammonia as one of the key steps in the biological nitrogen cycle, where it participates in the anaerobic energy metabolism of dissimilatory nitrate ammonification. Here we report on the crystal structure of this enzyme from the microorganism Sulfurospirillum deleyianum, which we solved by multiwavelength anomalous dispersion methods. We propose a reaction scheme for the transformation of nitrite based on structural and spectroscopic information. Cytochrome c nitrite reductase is a functional dimer, with 10 close-packed haem groups of type c and an unusual lysine-coordinated high-spin haem at the active site. By comparing the haem arrangement of this nitrite reductase with that of other multihaem cytochromes, we have been able to identify a family of proteins in which the orientation of haem groups is conserved whereas structure and function are not.

Structure of cytochrome c nitrite reductase.,Einsle O, Messerschmidt A, Stach P, Bourenkov GP, Bartunik HD, Huber R, Kroneck PM Nature. 1999 Jul 29;400(6743):476-80. PMID:10440380^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Einsle O, Messerschmidt A, Stach P, Bourenkov GP, Bartunik HD, Huber R, Kroneck PM. Structure of cytochrome c nitrite reductase. Nature. 1999 Jul 29;400(6743):476-80. PMID:10440380 doi:10.1038/22802

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 See Also
6 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qdb"

@@ Line 3: / Line 3: @@
 <StructureSection load='1qdb' size='340' side='right'caption='[[1qdb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1qdb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfurospirillum_deleyianum Sulfurospirillum deleyianum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QDB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QDB FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1qdb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurospirillum_deleyianum Sulfurospirillum deleyianum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QDB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QDB FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qdb OCA], [http://pdbe.org/1qdb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qdb RCSB], [http://www.ebi.ac.uk/pdbsum/1qdb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qdb ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qdb OCA], [https://pdbe.org/1qdb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qdb RCSB], [https://www.ebi.ac.uk/pdbsum/1qdb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qdb ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/NRFA_SULDE NRFA_SULDE]] Plays a role in nitrite reduction.[HAMAP-Rule:MF_01182]
+[[https://www.uniprot.org/uniprot/NRFA_SULDE NRFA_SULDE]] Plays a role in nitrite reduction.[HAMAP-Rule:MF_01182]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 31: / Line 31: @@
 ==See Also==
 *[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
+*[[Cytochrome c nitrite reductase|Cytochrome c nitrite reductase]]
 *[[Nitrite reductase 3D structures|Nitrite reductase 3D structures]]
 == References ==

1qdb

From Proteopedia

Revision as of 14:49, 3 March 2021

CYTOCHROME C NITRITE REDUCTASE

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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