6k4g

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==Crystal structure of the PI5P4Kbeta-GMPPNP complex==
==Crystal structure of the PI5P4Kbeta-GMPPNP complex==
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<StructureSection load='6k4g' size='340' side='right'caption='[[6k4g]]' scene=''>
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<StructureSection load='6k4g' size='340' side='right'caption='[[6k4g]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K4G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6K4G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6k4g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6K4G FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6k4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k4g OCA], [http://pdbe.org/6k4g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k4g RCSB], [http://www.ebi.ac.uk/pdbsum/6k4g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k4g ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3x04|3x04]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIP4K2B, PIP5K2B ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6k4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k4g OCA], [https://pdbe.org/6k4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6k4g RCSB], [https://www.ebi.ac.uk/pdbsum/6k4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6k4g ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN]] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]]
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[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Senda M]]
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[[Category: Senda, M]]
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[[Category: Senda T]]
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[[Category: Senda, T]]
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[[Category: Takeuchi K]]
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[[Category: Takeuchi, K]]
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[[Category: Lipid kinase]]
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[[Category: Phosphoinositide signaling]]
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[[Category: Transferase]]

Revision as of 14:52, 3 March 2021

Crystal structure of the PI5P4Kbeta-GMPPNP complex

PDB ID 6k4g

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