2fnp
From Proteopedia
(Difference between revisions)
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==Crystal structure of SarA== | ==Crystal structure of SarA== | ||
- | <StructureSection load='2fnp' size='340' side='right' caption='[[2fnp]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='2fnp' size='340' side='right'caption='[[2fnp]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2fnp]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2fnp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FNP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FNP FirstGlance]. <br> |
- | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sarA ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sarA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fnp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fnp OCA], [https://pdbe.org/2fnp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fnp RCSB], [https://www.ebi.ac.uk/pdbsum/2fnp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fnp ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/SARA_STAAW SARA_STAAW]] Global regulator with both positive and negative effects that controls the expression of several virulence factors and the biofilm formation process in a cell density-dependent manner (By similarity). Required for transcription of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus. Negatively regulates the expression of spa (protein A) and aur (metalloprotease aureolysin). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Cheung, A L]] | [[Category: Cheung, A L]] | ||
[[Category: Liu, Y]] | [[Category: Liu, Y]] |
Revision as of 15:30, 3 March 2021
Crystal structure of SarA
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Categories: Large Structures | Cheung, A L | Liu, Y | Manna, A C | Pan, C H | Zhang, G | Dna binding | Transcription | Wing-helix