Aldehyde dehydrogenase 3D structures

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 22: Line 22:
**[[3rhm]] - rALDH1 C- terminal<br />
**[[3rhm]] - rALDH1 C- terminal<br />
-
*ALDH class 1 A (retinal dehydrogenase)
+
*ALDH family 1 A (retinal dehydrogenase)
-
**[[5l2m]], [[5l2n]], [[5l2o]] – hRALDH1 + inhibitor<br />
+
**[[4x4l]], [[5l2m]], [[5l2n]], [[5l2o]], [[7jws]], [[7jwt]], [[7jwu]], [[7jwv]], [[7jww]] – hRALDH1A1 + inhibitor<br />
-
**[[5tei]], [[6dum]] – hRALDH1 + NAD + inhibitor<br />
+
**[[5tei]], [[6dum]] – hRALDH1A1 + NAD + inhibitor<br />
-
**[[6alj]], [[6b5g]], [[6b5h]], [[6b5i]] – hRALDH2 + NAD + inhibitor<br />
+
**[[6alj]], [[6b5g]], [[6b5h]], [[6b5i]] – hRALDH1A22 + NAD + inhibitor<br />
-
**[[5fhz]] – hRALDH3 + NAD + retinol<br />
+
**[[5fhz]] – hRALDH1A3 + NAD + retinol<br />
 +
**[[6s6w]], [[6te5]], [[6try]], [[7a6q]] – hRALDH1A3 + NAD + inhibitor<br />
 +
**[[5abm]] – sRALDHA1 + inhibitor<br />
*ALDH class 2
*ALDH class 2
Line 64: Line 66:
**[[5myp]] – TbALDH – ''Trypanosoma brucei''<br />
**[[5myp]] – TbALDH – ''Trypanosoma brucei''<br />
**[[5nno]] – TbALDH + NAD + inhibitor <br />
**[[5nno]] – TbALDH + NAD + inhibitor <br />
 +
 +
*ALDH family 4 (delta-1-pyrroline-5-carboxylate dehydrogenase)
 +
 +
**[[3v9g]], [[4oe5]] – hALDH4A1 <br />
 +
**[[3v9h]], [[3v9i]] – hALDH4A1 (mutant)<br />
 +
**[[3v9j]], [[4e3x]] – mALDH4A1 <br />
 +
**[[3v9k]] – mALDH4A1 + Glu<br />
 +
**[[4lh0]] – mALDH4A1 + glyoxylate<br />
 +
**[[4lh1]] – mALDH4A1 + malonate<br />
 +
**[[4lh2]] – mALDH4A1 + succinate<br />
 +
**[[4lh3]] – mALDH4A1 + glutarate<br />
 +
**[[4lgz]] – mALDH4A1 + acetate<br />
 +
**[[3v9l]] – mALDH4A1 + NAD<br />
 +
 +
*ALDH family 5 (succinate-semialdehyde dehydrogenase)
 +
 +
**[[2w8n]], [[2w8o]], [[2w8r]] – hALDH5A1 <br />
 +
**[[2w8p]] – hALDH5A1 (mutant)<br />
 +
**[[2w8q]] – hALDH5A1 + succinate<br />
 +
**[[3jz4]] - EcALDH5A1 + NADP<br />
 +
**[[4v6h]] - BpALDH5A1 – ''Burkholderia pseudomallei''<br />
 +
**[[3rh9]] - ALDH5A1 – ''Marinobacter aquaeolei''<br />
 +
 +
*ALDH family 7 (alpha-aminoadipic semialdehyde dehydrogenase)
 +
 +
**[[4zvw]], [[4zvx]], [[4zuk]] - hALDH7A1<br />
 +
**[[6o4d]] – hALDH7A1 + pipecolic acid<br />
 +
**[[2j6l]], [[4zvy]] – hALDH7A1 + NAD
 +
**[[6o4b]], [[6o4c]], [[6o4e]], [[6o4h]], [[6o4k]], [[6o4l]], [[6u2x]], [[6v0z]] – hALDH7A1 (mutant) + NAD<br />
 +
**[[6o4d]], [[6o4i]] – hALDH7A1 (mutant) + pipecolic acid<br />
 +
**[[4x0u]] - hALDH7A1 + inhibitor<br />
 +
**[[4zul]] - hALDH7A1 + a-aminoadipate<br />
 +
**[[6o4f]], [[6o4g]] - hALDH7A1 (mutant) + a-aminoadipate<br />
 +
**[[4x0t]] - hALDH7A1 + NAD+ inhibitor<br />
 +
 +
*ALDH family 9 (4-trimethylaminobutyraldehyde dehydrogenase)
 +
 +
**[[6qak]], [[6qao]], [[6qap]] – hALDH9A1 <br />
 +
**[[6vr6]], [[6vwf]] – hALDH9A1 + NAD<br />
*NAD-dependent ALDH
*NAD-dependent ALDH
-
**[[2w8n]], [[2w8o]], [[2w8r]] – Succinate–semi-hALDH family 5<BR />
 
-
**[[2w8p]] - Succinate–semi-hALDH family 5 (mutant) <BR />
 
-
**[[3r31]] – Betaine-ALDH – ''Agrobacterium tumefaciens''<BR />
 
-
**[[4mpb]], [[4nu9]], [[4q92]], [[4qto]] - Betaine-SaALDH – ''Staphylococcus aureus''<BR />
 
-
**[[4qje]] - Betaine-SaALDH (mutant)<br />
 
-
**[[4zxu]], [[4zwl]] - Betaine-SaALDH (mutant) + NAD<br />
 
-
**[[4cbb]], [[6bpg]] - Betaine-PaALDH - ''Pseudomonas aeruginosa''<br />
 
-
**[[6bjp]] - Betaine-PaALDH (mutant)<br />
 
-
**[[1a4s]] - Betaine-cALDH - cod<BR />
 
**[[3vos]], [[3tz6]], [[3vos]] – Aspartate-semi-MtALDH<BR />
**[[3vos]], [[3tz6]], [[3vos]] – Aspartate-semi-MtALDH<BR />
**[[2cq8]] - Formyltetrahydrofolate-hALDH PP-binding domain - NMR<BR />
**[[2cq8]] - Formyltetrahydrofolate-hALDH PP-binding domain - NMR<BR />
Line 93: Line 125:
*NAD-dependent ALDH binary complexes
*NAD-dependent ALDH binary complexes
-
**[[2w8q]] - Succinate–semi-hALDH family 5 + succinic acid<BR />
 
-
**[[4mpy]], [[4nea]] - Betaine-SaALDH + NAD<BR />
 
-
**[[4qn2]], [[5ez4]], [[5eyu]], [[5dib]] - Betaine-SaALDH (mutant) + NAD<br />
 
-
**[[1bpw]] - Betaine-cALDH + NAD<BR />
 
-
**[[4zvw]], [[4zvx]], [[4zuk]] - Aminoadipate-semi-hALDH family 7<br />
 
-
**[[2j6l]], [[4zvy]] – Aminoadipate-semi-hALDH family 7 + NAD<BR />
 
-
**[[6o4b]], [[6o4c]], [[6o4e]], [[6o4h]], [[6o4k]], [[6o4l]], [[6u2x]] – Aminoadipate-semi-hALDH family 7 (mutant) + NAD<br />
 
-
**[[6o4d]], [[6o4i]] – Aminoadipate-semi-hALDH family 7 (mutant) + pipecolic acid<br />
 
-
**[[4x0u]] - Aminoadipate-semi-hALDH family 7 + inhibitor<br />
 
-
**[[4zul]] - Aminoadipate-semi-hALDH family 7+ α-aminoadipate<br />
 
-
**[[6o4f]], [[6o4g]] - Aminoadipate-semi-hALDH family 7 (mutant) + α-aminoadipate<br />
 
**[[2cfi]] - Formyltetrahydrofolate-hALDH hydrolase domain + formyltetrahydropterin<BR />
**[[2cfi]] - Formyltetrahydrofolate-hALDH hydrolase domain + formyltetrahydropterin<BR />
**[[4a0m]], [[4v37]] – spALDH + NAD – spinach<br />
**[[4a0m]], [[4v37]] – spALDH + NAD – spinach<br />
Line 111: Line 132:
**[[3l4p]], [[1sij]] – ALDH + AsO3 – ''Desulfovibrio gigas''<br />
**[[3l4p]], [[1sij]] – ALDH + AsO3 – ''Desulfovibrio gigas''<br />
**[[3ju8]] - Succinylglutamic–semi-PaALDH + NAD <br />
**[[3ju8]] - Succinylglutamic–semi-PaALDH + NAD <br />
-
**[[4caz]] - Betaine-PaALDH + NAD derivative<br />
 
**[[4c3s]] - CpALDH + NAD <br />
**[[4c3s]] - CpALDH + NAD <br />
**[[5dbv]] - CpALDH + CoA <br />
**[[5dbv]] - CpALDH + CoA <br />
Line 129: Line 149:
**[[4i3x]] – SmALDH + phosphonoacete + NAD<br />
**[[4i3x]] – SmALDH + phosphonoacete + NAD<br />
**[[5jfm]] – RpALDH + CoA + propionyl-CoA<br />
**[[5jfm]] – RpALDH + CoA + propionyl-CoA<br />
-
**[[4x0t]] - Aminoadipate-semi-hALDH family 7 + NAD+ inhibitor<br />
 
*NADP-dependent ALDH
*NADP-dependent ALDH
Line 138: Line 157:
**[[2o2p]] – Formyltetrahydrofolate-rALDH C-terminal<br />
**[[2o2p]] – Formyltetrahydrofolate-rALDH C-terminal<br />
**[[2y51]], [[2y52]], [[2y53]], [[2y5d]] – BxALDH (mutant) – ''Burkholderia xenovorans''<br />
**[[2y51]], [[2y52]], [[2y53]], [[2y5d]] – BxALDH (mutant) – ''Burkholderia xenovorans''<br />
-
**[[4v6h]] - Succinate–semi-ALDH – ''Burkholderia pseudomallei''<br />
 
-
**[[3rh9]] - Succinate–semi-ALDH – ''Marinobacter aquaeolei''<br />
 
**[[3uw3]] - aspartate–semi-BtALDH – ''Burkholderia thailandensis''<br />
**[[3uw3]] - aspartate–semi-BtALDH – ''Burkholderia thailandensis''<br />
**[[3v4c]] - SmALDH<br />
**[[3v4c]] - SmALDH<br />
Line 154: Line 171:
**[[3b4w]] - MtALDH + NADP – ''Mycobacterium tuberculosis''<BR />
**[[3b4w]] - MtALDH + NADP – ''Mycobacterium tuberculosis''<BR />
**[[1eyy]], [[1ez0]] – ALDH + NADP – ''Vibrio harveyi''<br />
**[[1eyy]], [[1ez0]] – ALDH + NADP – ''Vibrio harveyi''<br />
-
**[[3jz4]] - Succinate–semi-EcALDH + NADP<br />
 
**[[3hsk]] - aspartate–semi-ALDH + NADP – ''Candida albicans''<br />
**[[3hsk]] - aspartate–semi-ALDH + NADP – ''Candida albicans''<br />
**[[4h73]], [[4nmj]], [[4nmk]], [[5f2c]], [[5exf]], [[5euy]], [[5ekc]], [[5ek6]] - PfALDH + NADP <br />
**[[4h73]], [[4nmj]], [[4nmk]], [[5f2c]], [[5exf]], [[5euy]], [[5ekc]], [[5ek6]] - PfALDH + NADP <br />
Line 175: Line 191:
**[[5iuw]] – PsIALDH + NAD + indole acetate<br />
**[[5iuw]] – PsIALDH + NAD + indole acetate<br />
-
*NAD-dependent glyceraldehydes-3-phosphate dehydrogenase
+
*NAD-dependent glyceraldehyde-3-phosphate dehydrogenase
**[[1vsu]] – CpGAPDH – ''Cryptosporidium parvum''<br />
**[[1vsu]] – CpGAPDH – ''Cryptosporidium parvum''<br />
Line 249: Line 265:
**[[1uxq]] - TtGAPDH (mutant) + NADP + G1P<br />
**[[1uxq]] - TtGAPDH (mutant) + NADP + G1P<br />
**[[1uxr]] - TtGAPDH (mutant) + NADP + F6P
**[[1uxr]] - TtGAPDH (mutant) + NADP + F6P
 +
 +
*NAD/NADP-dependent betaine ALDH
 +
 +
**[[1a4s]] - Betaine-cALDH – cod<br />
 +
**[[1bpw]] - Betaine-cALDH + NAD<br />
 +
**[[3r31]] – Betaine-ALDH – ''Agrobacterium tumefaciens''<br />
 +
**[[4mpb]], [[4nu9]], [[4q92]], [[4qto]] - Betaine-SaALDH – ''Staphylococcus aureus''<br />
 +
**[[4qje]] - Betaine-SaALDH (mutant)<br />
 +
**[[4zxu]], [[4zwl]] - Betaine-SaALDH (mutant) + NAD<br />
 +
**[[4cbb]], [[6bpg]] - Betaine-PaALDH - ''Pseudomonas aeruginosa''<br />
 +
**[[6bjp]] - Betaine-PaALDH (mutant)<br />
 +
**[[4mpy]], [[4nea]] - Betaine-SaALDH + NAD<br />
 +
**[[4qn2]], [[5ez4]], [[5eyu]], [[5dib]] - Betaine-SaALDH (mutant) + NAD<br />
 +
**[[4caz]] - Betaine-PaALDH + NAD derivative<br />
 +
**[[3k2w]] - Betaine-ALDH – ''Pseudoalteromonas atlantica''<br />
 +
**[[6wsa]] - Betaine-BpALDH<br />
 +
**[[6wsb]] - Betaine-BpALDH + NAD<br />
 +
**[[2wox]], [[2wme]], [[2xdr]], [[3zqa]] - Betaine-PaALDH + NADP<br />
*Uncharacterized ALDH
*Uncharacterized ALDH

Revision as of 11:03, 10 March 2021

3D Structures of Aldehyde dehydrogenase

Updated on 10-March-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

Retrieved from "http://52.214.119.220/wiki/index.php/Aldehyde_dehydrogenase_3D_structures"
Personal tools