User:Justin Smith/Sandbox 1

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== References ==
== References ==
Wang, L, Qian, H, Nian, Y, Han, Y, Ren, Z, Hanzhi, Z, Hu, L, Prasad, B.V., Laganowsky, A, Yan, N, Zhou, M. (2020). Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature, 581, 329-332.
Wang, L, Qian, H, Nian, Y, Han, Y, Ren, Z, Hanzhi, Z, Hu, L, Prasad, B.V., Laganowsky, A, Yan, N, Zhou, M. (2020). Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature, 581, 329-332.
 +
<ref name="wang">PMID:32433610</ref>.
Sui, X, Wang, K, Gluchowski, N, Elliott, S, Liao, M, Walther, T, Farese Jr, R. (2020). Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Nature, 581, 323-328.
Sui, X, Wang, K, Gluchowski, N, Elliott, S, Liao, M, Walther, T, Farese Jr, R. (2020). Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Nature, 581, 323-328.

Revision as of 20:06, 16 March 2021

Contents

DGAT Homo Sapien

Caption for this structure

Drag the structure with the mouse to rotate

Disease

Active Site

is the active base catalytic function

Relevance

Mecanism

Figure 1. Mecanism of base catalyized reaction
Figure 1. Mecanism of base catalyized reaction

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

References

Wang, L, Qian, H, Nian, Y, Han, Y, Ren, Z, Hanzhi, Z, Hu, L, Prasad, B.V., Laganowsky, A, Yan, N, Zhou, M. (2020). Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature, 581, 329-332. [1].

Sui, X, Wang, K, Gluchowski, N, Elliott, S, Liao, M, Walther, T, Farese Jr, R. (2020). Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Nature, 581, 323-328.

Rodriguez, A. M. (2020). Zooming in on the architecture of DGAT1, a transmembrane lipid factory. Baylor College of Medicine.

Stone, S. J. Mammalian Diacylglycerol Acyltransferases (DGAT). AOCS Lipid Library.

  1. Wang L, Qian H, Nian Y, Han Y, Ren Z, Zhang H, Hu L, Prasad BVV, Laganowsky A, Yan N, Zhou M. Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature. 2020 May;581(7808):329-332. doi: 10.1038/s41586-020-2280-2. Epub 2020 May, 13. PMID:32433610 doi:http://dx.doi.org/10.1038/s41586-020-2280-2

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