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6qgn

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<StructureSection load='6qgn' size='340' side='right'caption='[[6qgn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='6qgn' size='340' side='right'caption='[[6qgn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6qgn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6qgn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QGN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=J1W:2-Bromopalmitic+acid'>J1W</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J1W:2-Bromopalmitic+acid'>J1W</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgn OCA], [http://pdbe.org/6qgn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgn RCSB], [http://www.ebi.ac.uk/pdbsum/6qgn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgn ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LYPLA1, APT1, LPL1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgn OCA], [https://pdbe.org/6qgn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qgn RCSB], [https://www.ebi.ac.uk/pdbsum/6qgn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LYPA1_HUMAN LYPA1_HUMAN]] Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity.<ref>PMID:20418879</ref>
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[[https://www.uniprot.org/uniprot/LYPA1_HUMAN LYPA1_HUMAN]] Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity.<ref>PMID:20418879</ref>
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==See Also==
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*[[Thioesterase 3D structures|Thioesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Audagnotto, M]]
[[Category: Audagnotto, M]]

Revision as of 06:51, 17 March 2021

Crystal structure of APT1 bound to 2-Bromopalmitate

PDB ID 6qgn

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