7jnu

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==New condition to crystallize Thermoanaerobacter ethanolicus Secondary alcohol dehydrogenases I86A mutant with 2-pentanol and 3-methylcylohexanol==
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==Ternary complex crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus mutants C295 and I86A provides better understanding of catalytic mechanism==
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<StructureSection load='7jnu' size='340' side='right'caption='[[7jnu]]' scene=''>
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<StructureSection load='7jnu' size='340' side='right'caption='[[7jnu]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JNU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7JNU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7jnu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_31550 Atcc 31550]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JNU FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7jnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jnu OCA], [http://pdbe.org/7jnu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7jnu RCSB], [http://www.ebi.ac.uk/pdbsum/7jnu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7jnu ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2RP:(2R)-pentan-2-ol'>2RP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">adhB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1757 ATCC 31550])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alcohol_dehydrogenase_(NADP(+)) Alcohol dehydrogenase (NADP(+))], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.2 1.1.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jnu OCA], [https://pdbe.org/7jnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jnu RCSB], [https://www.ebi.ac.uk/pdbsum/7jnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jnu ProSAT]</span></td></tr>
</table>
</table>
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==See Also==
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*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 31550]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dinh T]]
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[[Category: Dinh, T]]
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[[Category: Phillips R]]
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[[Category: Phillips, R]]
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[[Category: Rahn K]]
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[[Category: Rahn, K]]
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[[Category: 2-pentanol]]
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[[Category: Nadp]]
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[[Category: Oxidoreductase]]
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[[Category: Secondary alcohol dehydrogenase]]

Revision as of 07:00, 17 March 2021

Ternary complex crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus mutants C295 and I86A provides better understanding of catalytic mechanism

PDB ID 7jnu

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