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2gwd

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==Crystal structure of plant glutamate cysteine ligase in complex with Mg2+ and L-glutamate==
==Crystal structure of plant glutamate cysteine ligase in complex with Mg2+ and L-glutamate==
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<StructureSection load='2gwd' size='340' side='right' caption='[[2gwd]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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<StructureSection load='2gwd' size='340' side='right'caption='[[2gwd]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2gwd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Braju Braju]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GWD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GWD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2gwd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Braju Braju]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GWD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gwc|2gwc]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2gwc|2gwc]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3707 BRAJU])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3707 BRAJU])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate--cysteine_ligase Glutamate--cysteine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.2 6.3.2.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutamate--cysteine_ligase Glutamate--cysteine ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.2 6.3.2.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gwd OCA], [http://pdbe.org/2gwd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gwd RCSB], [http://www.ebi.ac.uk/pdbsum/2gwd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gwd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gwd OCA], [https://pdbe.org/2gwd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gwd RCSB], [https://www.ebi.ac.uk/pdbsum/2gwd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gwd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GSH1_BRAJU GSH1_BRAJU]] Participates in the detoxification process.<ref>PMID:9620267</ref> <ref>PMID:9119067</ref>
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[[https://www.uniprot.org/uniprot/GSH1_BRAJU GSH1_BRAJU]] Participates in the detoxification process.<ref>PMID:9620267</ref> <ref>PMID:9119067</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Braju]]
[[Category: Braju]]
[[Category: Glutamate--cysteine ligase]]
[[Category: Glutamate--cysteine ligase]]
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[[Category: Large Structures]]
[[Category: Gromes, R]]
[[Category: Gromes, R]]
[[Category: Hothorn, M]]
[[Category: Hothorn, M]]

Revision as of 07:25, 17 March 2021

Crystal structure of plant glutamate cysteine ligase in complex with Mg2+ and L-glutamate

PDB ID 2gwd

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