7m2l

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Revision as of 05:33, 24 March 2021 (edit) OCA (Talk | contribs) (New page: '''Unreleased structure''' The entry 7m2l is ON HOLD until Sep 16 2022 Authors: Hilario, E., Dunn, M.F., Mueller, L.J. Description: The internal aldimine form of the wild-type Salmonel...) ← Previous diff

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Revision as of 05:33, 24 March 2021

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Unreleased structure

The entry 7m2l is ON HOLD until Sep 16 2022

Authors: Hilario, E., Dunn, M.F., Mueller, L.J.

Description: The internal aldimine form of the wild-type Salmonella Typhimurium Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor at the alpha-and beta-site, sodium ion at the metal coordination site, and another F6F molecule at the enzyme beta-site at 1.60 Angstrom resolution. Two of the beta-Q114 rotamer conformations allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring