Sandbox Reserved 1673
From Proteopedia
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== Relevance == | == Relevance == | ||
- | Alginate lyase has two domains with Cyclic – C2 symmetry. Its secondary structure is roughly 14% helices and 44% beta strands. Both domains each consist of 7 helices and 15 beta strands with one disulfide bridge. The most <scene name='87/873235/Important_residues_view/1'>important residues</scene> for binding substrate as well as those involved in catalysis all lie on beta strands in both domains. | ||
== Structural highlights == | == Structural highlights == | ||
+ | Alginate lyase has two domains with Cyclic – C2 symmetry. Its secondary structure is roughly 14% helices and 44% beta strands. Both domains each consist of 7 helices and 15 beta strands with one disulfide bridge. The most <scene name='87/873235/Important_residues_view/1'>important residues</scene> for binding substrate as well as those involved in catalysis all lie on beta strands in both domains. | ||
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. |
Revision as of 02:51, 29 March 2021
This Sandbox is Reserved from 01/25/2021 through 04/30/2021 for use in Biochemistry taught by Bonnie Hall at Grand View University, Des Moines, USA. This reservation includes Sandbox Reserved 1665 through Sandbox Reserved 1682. |
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Xu F, Chen XL, Sun XH, Dong F, Li CY, Li PY, Ding H, Chen Y, Zhang YZ, Wang P. Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the Arctic. J Biol Chem. 2020 Sep 23. pii: RA120.015106. doi: 10.1074/jbc.RA120.015106. PMID:32967968 doi:http://dx.doi.org/10.1074/jbc.RA120.015106