User:Kaitlyn Roberts/Sandbox 1

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==Introduction==
==Introduction==
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Sterol O-acyltransferase(SOAT), otherwise known as Acyl-coenzyme A:cholesterol acyltransferase(ACAT), is an enzyme that catalyzes the esterification of cholesterol for efficient storage within the cell. Cholesterol is a membrane lipid that plays an essential role in maintaining the fluidity and integrity of the membrane; and cholesteryl esters are formed when an excess of cholesterol is present.
[[Image:Dimer side.png|400 px|right|thumb|Figure 1. The coolest image of this protein EVAH!!!]]
[[Image:Dimer side.png|400 px|right|thumb|Figure 1. The coolest image of this protein EVAH!!!]]
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==Function==
==Function==

Revision as of 13:55, 30 March 2021

Human Sterol O-acyltransferase

PDB ID 6p2p

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References

  1. 1.0 1.1 Guan C, Niu Y, Chen SC, Kang Y, Wu JX, Nishi K, Chang CCY, Chang TY, Luo T, Chen L. Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nat Commun. 2020 May 18;11(1):2478. doi: 10.1038/s41467-020-16288-4. PMID:32424158 doi:http://dx.doi.org/10.1038/s41467-020-16288-4

Student Contributors

  • Kylie Pfifer
  • Stepahnie Pellegrino
  • Kaitlyn Roberts

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Kaitlyn Roberts

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