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User:Tori Templin/Sandbox 1
From Proteopedia
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<scene name='87/877626/Overlay/6'>Overlay</scene> | <scene name='87/877626/Overlay/6'>Overlay</scene> | ||
<scene name='87/877626/Overlay/8'>CI976 vs. Inhibitor</scene> | <scene name='87/877626/Overlay/8'>CI976 vs. Inhibitor</scene> | ||
| + | [[Image: Screen Shot 2021-03-30 at 3.56.14 PM|300 px|right|thumb|Figure 2. CI-976 Inhibitor]] | ||
[[Image: CI-976.jpg|300 px|right|thumb|Figure 2. CI-976 Inhibitor]] | [[Image: CI-976.jpg|300 px|right|thumb|Figure 2. CI-976 Inhibitor]] | ||
</StructureSection> | </StructureSection> | ||
Revision as of 19:59, 30 March 2021
Acyl-Coenzyme A Cholesterol Acyltransferase
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References
- ↑ Farese RV Jr. The nine lives of ACAT inhibitors. Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1684-6. doi:, 10.1161/01.ATV.0000227511.35456.90. PMID:16857957 doi:http://dx.doi.org/10.1161/01.ATV.0000227511.35456.90
- ↑ Guan C, Niu Y, Chen SC, Kang Y, Wu JX, Nishi K, Chang CCY, Chang TY, Luo T, Chen L. Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nat Commun. 2020 May 18;11(1):2478. doi: 10.1038/s41467-020-16288-4. PMID:32424158 doi:http://dx.doi.org/10.1038/s41467-020-16288-4
- ↑ Qian H, Zhao X, Yan R, Yao X, Gao S, Sun X, Du X, Yang H, Wong CCL, Yan N. Structural basis for catalysis and substrate specificity of human ACAT1. Nature. 2020 May;581(7808):333-338. doi: 10.1038/s41586-020-2290-0. Epub 2020 May, 13. PMID:32433614 doi:http://dx.doi.org/10.1038/s41586-020-2290-0
Student Contributors
- Tori Templin
- Haylie Moehlenkamp
- Megan Fleshman
